http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-029818-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ef2dc8df44332274246a8699d1d2551 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate | 2001-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82dc6f08b2d1fcf52649e34ed59d0886 |
| publicationDate | 2003-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-029818-A1 |
| titleOfInvention | ADEQUATE PHARMACEUTICAL COMPOSITION FOR PROLONGED TREATMENT OR PROFILACTIC CARE OF OCULAR HYPERTENSION AND GLAUCOMA AND USE OF A COMPOSITE RELATED TO PROSTAGLANDINAS TO PRODUCE |
| abstract | A pharmaceutical composition suitable for the prolonged treatment or prophylactic care of ocular hypertension and glaucoma in a human patient by means of prolonged topical ocular administration comprising a compound related to prostaglandins as an active ingredient. Said compound has the formula (1), wherein W1, W2 and W3 are carbon or oxygen atoms; L, M and N are a hydrogen atom, hydroxy, a halogen atom, lower alkyl, lower alkoxy, hydroxyalkyl (lower), or oxo, wherein at least one of L and M is a different group of hydrogen, and the five-member ring may have at least one double bond; A is -CH2OH, -COCH2OH, -COOH or a functional derivative thereof; B is a single bond, -CH2-, -CH2-CH2-, -CH = CH-, -C ::: C, -CH2-CH2-CH2-, -CH = CH-CH2-, -CH2-CH = CH-, -C ::: C-CH2-, or -CH2-C ::: C-; R1 is a lower or middle aliphatic hydrocarbon residue, bivalent, saturated or unsaturated, which is unsubstituted or substituted by halogen, an alkyl, hydroxy, oxo, aryl group or a heterocyclic group; and Ra is a lower or middle aliphatic hydrocarbon residue, saturated or unsaturated, which is unsubstituted or substituted with a halogen, oxo, hydroxy, lower alkyl, lower alkoxy, lower alkanoyloxy, cycloalkyl (lower), cycloalkyloxy ( lower), aryl, aryloxy, a heterocyclic group or a heterocyclic-oxy group; cycloalkyl (lower); cycloalkyloxy (lower); aryl; aryloxy; a heterocyclic group or a heterocyclic-oxy group. The functional derivative of A may comprise salts, ethers, esters and amides. Use of the prostaglandin-related compound to produce said pharmaceutical composition. |
| priorityDate | 2000-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.