| abstract |
Compounds of the formula (1) as well as their salts with mineral or organic acids, their solvates and / or their hydrates, which have a strong affinity and a great selectivity towards the human NK1 receptors of the substance P. Preparation procedure, its compounds intermediaries of formula (IV), (VI) and (VIII) useful for their preparation, the pharmaceutical compositions containing them and their use for the manufacture of drugs intended to treat any pathology where Substance P and / or human NK1 receptors are applied . |