http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-019790-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02 |
filingDate | 1999-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-019790-A2 |
titleOfInvention | COMPOUNDS DERIVED FROM ERYTHROMYCIN, COMPOSITIONS THAT CONTAIN THEM. USE TO PREPARE A MEDICINAL PRODUCT |
abstract | A compound of the formula (1) or a pharmaceutically acceptable salt thereof, wherein R is a C3-8 alkyl group branched into alpha, alkenyl, alkynyl, alkoxyalkyl or alkylthioalkyl, any of which may be optionally substituted with one or more groups hydroxyl; a C5-8 cycloalkylalkyl group in which the alkyl group is a C2-5 alkyl group branched into alpha; a C3-8 cycloalkyl or C5-8 cycloalkenyl group, any of which may be optionally substituted with methyl groups, or one or more hydroxyl, or one or more C1-4 alkyl groups or halogen atoms; or a 3-6 heterocyclic ring containing oxygen or sulfur that may be saturated or totally or partially unsaturated and may be optionally substituted with one or more C1-4 alkyl groups or halogen atoms; or R is phenyl which may be optionally substituted with at least one substituent selected from the groups C1-4alkyl, C1-4alkoxy, C1-4alkylthio, halogen atoms, hydroxyl groups, trifluoromethyl and cyano; or R may have the formula (2) in which X1 is O, S or -CH2-; a, b, c and d are each independently selected from an integer that ranges between 0 and 2 and a + b + c + d <o = 5; or R is CH2R24, where R24 is H, C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, alkoxyalkyl or alkylthioalkyl containing C1-6 in each alkyl or alkoxy group, where any of said alkyl, alkoxy, alkenyl groups or alkynyl may be substituted by one or more hydroxyl groups or by one or more halogen atoms; or a C3-8 cycloalkyl or C5-8 cycloalkenyl, any of which may be optionally substituted by methyl or one or more C1-4 alkyl groups or halogen atoms; or a 3- to 6-membered heterocycle containing oxygen or sulfur, which may be saturated or totally or partially unsaturated and may optionally be substituted by one or more C1-4 alkyl groups or halogen atoms; or a group of the formula SR23, wherein R23 is C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, C3-8 cycloalkyl, C5-8 cycloalkenyl, phenyl or substituted phenyl, wherein the substituent is C1-4 alkyl, alkoxy C1-4 or halo, or a ring |
priorityDate | 1998-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.