http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-019787-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 1999-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-019787-A2 |
| titleOfInvention | MACROLID COMPOUNDS, THEIR USE IN THE PREPARATION OF MEDICINES, COMPOSITIONS AND METHOD FOR THE PREPARATION OF THE SAME |
| abstract | A compound of formula (1) R20 = H or formula (2) or a pharmaceutically acceptable salt thereof, wherein: Y is H, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, - (CH2) m ( C6-10 aryl), - (CH2) m (5-10 link heteroaryl), where m is an integer ranging from 0 to 4 and where the alkyl, alkenyl, aryl, heteroaryl and alkynyl groups are optionally substituted by 1 to 3 substituents independently selected from halogen, cyano, nitro, trifluoromethyl, azido, -C (O) R21, -OC (O) R21, -NR21C (O) R22, -C (O) NR21R22, hydroxy, C1-6 alkyl, alkoxy C1-6, C6-10 aryl and heteroaryl of 5 to 10 links; R1 is a branched alkyl, alkenyl, alkynyl, alkoxyalkyl or C3-8 alkylthioalkyl group, any of which may be optionally substituted by one or more hydroxyl groups; a C5-8 cycloalkylalkyl group in which the alkyl group is an alpha-branched C2-5 alkyl group; a C3-8 cycloalkyl or C5-8 cycloalkenyl group, any of which may be optionally substituted by methyl or one or more hydroxyl or one or more C1-4 alkyl groups or halogen atoms; or a heterocyclic ring containing oxygen or sulfur of 3 to 6 links that can be saturated or, totally or partially unsaturated and which may be optionally substituted by one or more C1-4 alkyl groups or halogen atoms; or R1 is phenyl which may be optionally substituted with at least one substituent selected from C1-4 alkyl, C1-4 alkoxy and thio (C1-4 alkyl) thio groups, halogen atoms, hydroxyl, trifluoromethyl and cyano groups; or R1 may be a group with a formula (3) in which X is O, S or -CH2-; a, b, c and d are each, independently 0 to 2 and a + b + c + d <o = 5; or R1 is CH2R24, where R24 is H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, alkoxyalkyl or alkylthioalkyl, containing C1-6 in each of the alkyl or alkoxy groups, any of said alkyl groups being able to be , alkoxy, alkenyl or alkynyl substituted by one or more hydroxyl groups or by one or more halogen atoms; or a C3-6 cycloalkyl or C3-6 cycloalkenyl, any of which may be optionally substituted by methyl or one or more C1-4 alkyl groups or atoms of |
| priorityDate | 1998-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.