abstract |
An amide derivative represented by the formula (I) included, wherein the B ring is heteroaryl; X is a bond or a lower alkylene group; and Res is a hydrogen atom, a halogen atom, a lower alkyl group, an amino, ungrup or aryl-lower alkyl group or a haloaryl-lower alkyl group, or a salt thereof. Likewise, there is a therapeutic agent for diabetes mellitus that has both a promoter action for insulin secretion and an action that enhances the sensitivity of insulin, in addition to having an action against obesity and against hyperlipidemia due to a selective stimulation action for Beta-3 receptors |