| abstract |
The present application describes nitrogen-containing heteroarommatic and derivatives thereof of the formula (I) where W is selected from the pyrazole, tetrazole, isoxazoline and triazole groups; DE is selected from the group consisting of isoquinolyl or, amino-isoquinolyl, amino-benzimidazolyl, amino-indazolyl, amino-benzisoxazolyl, quinolyl, diaminoquinazolyl, amno-quinazolyl, amino-phthalazinyl, tetrahydro-isoquinolyl and amino-methyl-naphthalyl; A selected from the groups: phenyl, piri dyl, isoquinolyl and pyrimidyl; and B is selected from the groups: phenyl, pyrrolidino, morpholino, imidazolyl, Benzimidazolyl, pyridyl and pyrimidyl. It is a compound s factor Xa inhibitors. |