http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-014960-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cf7f3f36d20185ce15a2d1f04d5fdc1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-14 |
| filingDate | 1999-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2001-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-014960-A1 |
| titleOfInvention | DERIVATIVES OF CARBOXILICO ACID PIRIMIDIN 5-REPLACED, ITS USE, PHARMACEUTICAL COMBINATIONS THAT UNDERSTAND AND PHARMACEUTICAL COMPOSITIONS CONTAINING DERIVATIVES |
| abstract | 2-Pyrimidine carboxylic acid derivatives of the formula (I) in which the substituents have the following meanings: R1 means tetrazol or a group of formula (II), R means a) an OR7 radical, where R7 means: hydrogen, the cation With an alkali metal, the cation of an alkaline earth metal, physiologically tolerated organic ammonium bond, such as C1-C4-tertiary alkylammonium or the ammonium ion. C3-8-cycloalkyl, C1-8-alkyl, CH2-phenyl, which may be substituted by one ovaries of the following radicals: hydrogen, nitro, cyano, C1-4-alkyl, C1-4-halogenoalkyl, hydroxy, C1-4 -alkoxy, mercapto, C1-4-alkylthio, amino NH (C1-4alkyl), N (C1-4-alkyl) 2, a C3-6-alkenyl group or a C3-6-alkynyl group, the groups of which can in turn carrying from one to five halogen atoms, R7 can also be a phenyl radical that can carry one to five halogen atoms and / or one to three of the following radicals: nitro, cyano, C1-4-alkyl, C1- 4 halogenoalkyl, hydroxy, C1-4-alkoxy, mercapto, C1-4alkylthio, amino, NH (C1-4-alkyl) 2, b) a heteroaromatic of cincomiembros linked by way of a nitrogen atom, as for example. pyrrolyl, pyrazolyl, imidazolyl and triazolyl, which can carry one or two halogen atoms or, or one to two C1-4-alkyl groups or one to two C1-4-alkoxy groups, c) a group of formula (III) in the that k can have the values 0, 1 and 2, p the values 1, 2,3 and 4 and R8 means C1-4-alkyl, C3-8-cycloalkyl, C3-6-alkenyl, C3-6alkynyl or phenyl, which may be substituted by one or more, e.g. one to three of the following radicals: hydrogen, nitro, cyano, C1-4-alkyl, C1-4-halogenoalkyl, hydroxy, C1-4 alkoxy, C1-4-alkylthio, mercapto, amino, NH (C1-C4-alkyl) , N (C1-C4-alkyl) 2, d) a radical of formula (IV), where R9 means: C1-4-alkyl, C3-6-alkenyl, C3-6-alkynyl, C3-8-cycloalkyl, being able These radicals carry a C1-4-alkoxy, C1-4-alkylthio radical and / or a phenyl radical, such as those mentioned in c), which may be substituted by one to three of the following radicals: hydrogen, nitro, cyano, C1- 4-alkyl, C1-4-halogenoalkyl, hydroxy, C1-4-alkoxy, C1-4-alkylthio, mercapto, amino, NH (C1-4-alkyl) |
| priorityDate | 1998-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.