http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-013119-A1

Outgoing Links

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filingDate 1998-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2000-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AR-013119-A1
titleOfInvention DERIVATIVES OF PIRIMIDINE -2,4,6-TRIONA, PROCESSES FOR ITS PRODUCTION AND PHARMACEUTICAL PREPARATIONS THAT CONTAIN THEM
abstract The present invention therefore relates to substances of the general formula I, wherein R1 and R2, independently of each other, can be H, alkenyl or alkyl; R3 represents a group WV where W represents a bond or a linear or branched alkyl or alkenyl group which can be optionally interrupted by oxygen, sulfur or nitrogen, which can be substituted by hydroxy, amino, mercapto, alkoxy, oxo, carboxy, acyl groups , alkyl, aralkyl, aryl or heteroaryl and V represents H, a saturated or unsaturated monocyclic or bicyclic ring that may optionally contain 1 to 4 nitrogen, oxygen or sulfur atoms and can be optionally substituted by hydroxy, amino, mercapto, alkoxy, oxo groups. , carboxy, acyl, acylamido, alkyl, aralkyl, aryl, or heteroaryl; R4 can be a residue -N (R13) -C (O) -R5, N (R13) - C (O) -OR5, N (R13) -SO2-R5, -N (R13) -C (S) - R5, N- (R13) -C (S) -OR5, -N (R13) -C (O) -CR14R15 (CR15R17) nC (O) -R5 or -N (R13) -CR14R15 (-CR16R17) nC ( O) -R18 each of which can be linked to the central pyrimidine ring through the nitrogen atom; n equals 0 or 1; R13 has the meaning mentioned above for R3 or optionally forms a 4- to 7-membered heterocycle of R14 or R16; and R5 represents an alkyl, cycloalkyl, aralkyl, aryl or heteroaryl residue where these residues can be substituted by hydroxy or amino or halogen groups, R14, R15, R16 and R17 independently of one another denote hydrogen, a C alpha idu residue of a proteinogenic amino acid, alkyl, cycloalkyl, aryl heteroaryl, aralkyl, or heteroalralkyl; R14 and R15 or alternatively R16 and R17 may together form a 3- to 7-membered carbocycle R18 denotes OH or N (R6R7) where R6 is equal to H or may be alkyl, cycloalkyl, aralkyl or heteroaryl and R7 represents a group which together with the
priorityDate 1997-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 33.