http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-013076-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2b9dc89cc4ba060cc73bbf0c90bbb78 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 1998-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2000-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-013076-A1 |
| titleOfInvention | NEW COMPOUNDS OF PIPERAZINE, A PROCEDURE FOR ITS PREPARATION AND A PHARMACEUTICAL COMPOSITION THAT INCLUDES THEM |
| abstract | Piperazine compounds of formula (I), procedures for their preparation, and a pharmaceutical composition for use as agents for the central nervous system (CNS) are described, in which Ra is a group of formula (i), in which P1 it is phenyl, aryl, bicyclic, a 5-7 membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur, or a bicyclic heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur; R1 is hydrogen, halogen, C1-6 alkyl, C3-6 cycloalkyl, CO-C1-6 alkyl, C1-6 alkoxy, hydroxy, hydroxy-C1-6 alkyl, hydroxy-C1-6 alkoxy, C1-6 alkoxy-alkoxy C1-6, acyl, nitro trifluoromethyl, cyano, SR9, SOR9, SO2R9, SO2NR10R11, CO2R10, CONR10R11, CO2NR10R11, CONR10 (CH2) cCO2R11, (CH2) cNR10R11, (CH2) cCONR10 R11, (CH2R), (CH2R) 2CO2-C1-6 alkyl, CO2 (CH2) cOR10, NR10R11, NR10CO2R11, NR10CONR10R11, CR10 = NOR11, NR10COOR11, CNR10 = NOR11, where R10 and R11 are independently hydrogen or C1-6 alkyl and c is 1 to 4; R2 is hydrogen, halogen, C1-6 alkyl, C3-6 cycloalkyl, C3-6 cycloalkenyl, C1-6 alkoxy, C1-6 alkanoyl, aryl, acyloxy, hydroxy, nitro, trilfuoromethyl, cyano, CO2R10, CONR10R11, NR10R11, where R10 and R11 are as defined for R1; a is 1, 2 or 3; or Ra is a group of formula (ii), in which P2 and P3 are independently phenyl, aryl, bicyclic, a 5- to 7-membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, or a group bicyclic heterocyclic containing 1 to 3 heteroatoms selected from oxygen, nitrogen or sulfur; A is a bond or oxygen, S (O) m where m is 0 to 2, carbonyl, CH2, -CH2CH2-, or NR4 where R4 is hydrogen or C1-6 alkyl; R1 is as defined above for the formula |
| priorityDate | 1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.