http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-012660-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 |
filingDate | 1998-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2000-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-012660-A1 |
titleOfInvention | USE OF QUINAZOLINE COMPOUNDS FOR THE MANUFACTURE OF A MEDICINE USEFUL FOR THE TREATMENT OF POLYCHYSTIC DISEASES OF THE KIDNEY. |
abstract | Use of quinazoline compounds for the manufacture of a medicament useful to treat or inhibit polycystic kidney diseases comprising an effective amount of a compound of formula 1; where X is phenyl optionally substituted with one or more substituents selected from the group consisting of halogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms; hydroxy, trifluoromethyl, cyano, nitro, carboxy, carboalcoxide 2-7 carbon atoms, carboalkyl 2-7 carbon atoms, amino and alkanoylamino 1-6 carbon atoms; R and R1 are each independently hydrogen, halogen, C 1-6 alkyl, C 1-6 alkoxy, hydroxy, or trifluoromethyl; R 2 is hydrogen, C 1-6 alkyl, C 1 -alkoxy -6 carbon, hydroxy or trifluoromethyl atoms; Y is a radical selected from the group consisting of formula 2; R3 is independently hydrogen, alkyl of 1-6 carbon atoms, formula 3; R3 is independently hydrogen, C 1-6 alkyl, carboxy, C 1-6 carboalkoxy, phenyl or C 2-7 carboalkyl; n = 2-4 or a pharmaceutically acceptable salt thereof, with the proviso that each R3 of Y may be the same or different. |
priorityDate | 1997-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.