http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-011776-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0264ab149dd139d522f7f14b1a3ea9e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 |
| filingDate | 1998-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2000-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-011776-A1 |
| titleOfInvention | A PHARMACEUTICAL ACCOMPOSITION TO TREAT DISORDERS OF APPETITION FOR THE CONSUMPTION OF CARBOHYDRATES OR ALCOHOLS |
| abstract | Use of a CBI central cannabinoid receptor antagonist, alone or in association with a metabolic disorder regulating compound, especially a beta3-adrenergic receptor agonist, for the preparation of drugs useful in the treatment of appetite disorders. For reference, the CBI receptor antagonist is a compound of formula (II), in which: R1 represents hydrogen, a fluorine, a hydroxy, a (C1-C5) alkoxy, a (C1-C5) alkylthio ,, a hydroxy (C1-C5) alkoxy, a -NR10R11 group, a cyano, a (C1-C5) alkylsulfonyl or a (C1-C5) alkylsulfinyl; R2 and R3 represent a (C1-C4) alkyl or together with the nitrogen atom to which they are attached, constitute a 5- to 10-membered, saturated or unsaturated, heterocyclic radical, not substituted or substituted one or more by a (C1-C3) alkyl or by a (C1-C3) alkoxy; R4, R5, R6, R7, R8, R9 each independently represent hydrogen, a halogen or untrifluoromethyl, and when R1 represents a fluorine, R4, R5, R6, R7, R8 and / or R9 can equally represent a fluoromethyl; provided that at least one of the R4 or R7 substituents is different from hydrogen; R10 and R11 each represent independently, hydrogen or a (C 1 -C5) alkyl or R10 and R11 together with the nitrogen atom to which they are attached, constitute a heterocyclic radical chosen from pyrrolidin-1-yl, piperidin-1-yl, morpholin -4-yl and piperazin-1-yl, not substituted or substituted by a (C1-C4) alkyl; one of their salts or one of their solvates. A pharmaceutical composition containing a CBI receptor antagonist and a regulator of metabolic functions with a pharmaceutical excipient and a multi-compartment device or K IT for the treatment of appetite disorders containing: an antagonist of the |
| priorityDate | 1997-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.