http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-011546-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ccd0fc6e3476a4ff8053818414a086f8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-222 |
filingDate | 1998-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2000-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-011546-A1 |
titleOfInvention | USE OF COMPOUNDS THAT ARE AGONISTS OF BETA 3 ADRENERGIC RECEPTORS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL COMPOSITIONS |
abstract | Use of Beta3-agonist compounds (compounds that are beta-3 adrenergic receptor agonists) for the preparation of pharmaceutical compositions intended to accelerate wound healing, particularly for the preparation of healing drugs, more particularly, for the preparation of pharmaceutical compositions intended to speed up the healing of lower limb sores in diabetic mammals. Some useful beta3-agonists are represented by formula (I), in which: X represents hydrogen, a halogen, a trifluoromethyl group or a (C1-C4) alkyl group; R represents hydrogen, a methyl group, unsubstituted or substituted by a carboxy or lower carbalkoxy group or one of its pharmaceutically acceptable salts. Other useful beta3-agonists are represented by formula (II), in which: n is 1, 2 or 3; A represents a benzofuran-2-yl group or a phenyl group unsubstituted or substituted by one or two halogen atoms or by a (C1-C4) alkyl or trifluoromethyl group; R1 represents: a hydrogen, a (C1-C6) alkyl group, a functional group chosen from the following groups: hydroxy, (C1-C6) alkoxy, (C2-C6) alkenyloxy, (C2-C6) alkynyloxy, (C3-C8 ) cycloalkyloxy, (C3-C8) cycloalkyl (C1-C6) alkoxy, benzyloxy, phenoxy, mercapto, (C1-C6) alkylthio, (C2-C6) alkenylthio, (C2-C6) alkynylthio, (C3-C8) cycloalkylthio, (C3-C8) cycloalkyl (C1-C6) alkylthio, benzylthio, phenylthio, ((C1-C6) alkyl) sulfinyl, ((C2-C6) alkenyl) sulfinyl, ((C2-C6) alkynyl) sulfinyl, (C3- C8) cycloalkylsulfinyl, ((C3-C8) cycloalkyl (C1-C6) alkyl) sulfinyl, benzylsulfinyl, phenylsulfinyl, ((C1-C6) alkyl) sulfonyl, ((C2-C6) alkenyl) sulfonyl; ((C2-C6) alkynyl) sulfonyl, ((C3-C8) cycloalkylsulfonyl, ((C3-C8) cycloalkyl (C1-C6) alkyl) sulfonyl, |
priorityDate | 1997-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.