http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-010077-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-353 |
| filingDate | 1997-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2000-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-010077-A1 |
| titleOfInvention | PROCEDURE FOR THE RACEMIZATION OF SUBSTITUTED 4-CETO-CARBOXYLIC ACIDS |
| abstract | Procedure for the racemization of compounds of formula (I), in which: R1 is aryl, substituted aryl or diaryl, substituted diaryl; R2 is hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl; R3 is alkyl, substituted alkyl, branched alkyl, alkenyl, substituted alkenyl, where they are racemized in an acidic medium. It refers to a new type procedure for the racemization of substituted 4-ketocarboxylic acids. The procedure constitutes an economical new way for the recycling of an inactive enantiomer to the synthesis sequence and, therefore, will increase the overall yield. Substituted 4-ketocarboxylic acids, especially substituted aryl- and biaryl-4-ketocarboxylic acids, are inhibitors of enzymes of the matrix metalloproteinase class. By inhibiting the enzymes mentioned above, for example, osteoarthritis, rheumatoid arthritis and metastasis can be combated. |
| priorityDate | 1996-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458392451 |
Total number of triples: 16.