http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-009899-A1

Outgoing Links

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00
filingDate 1998-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2000-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AR-009899-A1
titleOfInvention COMPOUNDS OF 7-PHENYL-1,4-DIAZEPAN, WITH ANTAGONISTIC NEUROQUININE ACTIVITY, PROCEDURE AND INTERMEDIARIES FOR ITS PREPARATION, AND CONTAINING MEDICINES.
abstract Compounds with neurokinin antagonistic activity of the general formula (I), wherein R1 signifies hydrogen or lower alkyl; R2 means hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl and R3 means hydrogen, lower alkyl, lower alkoxy, halogen or otrifluoromethyl, or R2 and R3 are common 1 to 2-carbon-alkylenedioxy attached to contiguous carbon atoms of the ring of phenyl; R4 signifies hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; and R5 signifies hydrogen, lower alkyl, lower alkoxy, halogen, otrifluoromethyl; or R4 and R5 in common signify alkylene dioxy with 1 to 2 carbon atoms attached to adjacent carbon atoms of the phenyl ring; R6 means lower alkyl, halogen or trifluoromethyl; R7 signifies lower alkyl, halogen or trifluoromethyl; A means a group - (CH2) n, where it represents an integer from 1 to 3, or means a group -NH- (CH2) m, where m represents an integer from 2 to 3; and B means a 1 to 3 carbon atom alkylene chain, optionally substituted with lower alkyl, as well as its physiologically compatible salts and intermediary procedures for the preparation of these compounds.
priorityDate 1997-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 27.