http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-009899-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34c531b0dce54fb192c75fd1f4f8d473 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 |
filingDate | 1998-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2000-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-009899-A1 |
titleOfInvention | COMPOUNDS OF 7-PHENYL-1,4-DIAZEPAN, WITH ANTAGONISTIC NEUROQUININE ACTIVITY, PROCEDURE AND INTERMEDIARIES FOR ITS PREPARATION, AND CONTAINING MEDICINES. |
abstract | Compounds with neurokinin antagonistic activity of the general formula (I), wherein R1 signifies hydrogen or lower alkyl; R2 means hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl and R3 means hydrogen, lower alkyl, lower alkoxy, halogen or otrifluoromethyl, or R2 and R3 are common 1 to 2-carbon-alkylenedioxy attached to contiguous carbon atoms of the ring of phenyl; R4 signifies hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl; and R5 signifies hydrogen, lower alkyl, lower alkoxy, halogen, otrifluoromethyl; or R4 and R5 in common signify alkylene dioxy with 1 to 2 carbon atoms attached to adjacent carbon atoms of the phenyl ring; R6 means lower alkyl, halogen or trifluoromethyl; R7 signifies lower alkyl, halogen or trifluoromethyl; A means a group - (CH2) n, where it represents an integer from 1 to 3, or means a group -NH- (CH2) m, where m represents an integer from 2 to 3; and B means a 1 to 3 carbon atom alkylene chain, optionally substituted with lower alkyl, as well as its physiologically compatible salts and intermediary procedures for the preparation of these compounds. |
priorityDate | 1997-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.