| abstract |
They correspond to formula (1) where x is selected from the group consisting of figure (2) where: Y is uncle, oxy or a methylene group; Z is hydrogen or -C (O) - (CH2) m-Q, where Q is hydrogen or -COOH and m is an integer of 1, 2, 3 or 4; R1 is C1-C6 alkyl; or a stereoisomer thereof. The use of such compounds for the manufacture of medicaments for the treatment of inhibition of LDL-lipid peroxidation for the treatment of reduction of plasma cholesterol level, inhibition of cytokine-induced expression of the molecule is also described. -1 of vascular adhesioncell and / or intercellular adhesion molecule-1 and of a chronic inflammatory disease. |