| abstract |
It refers to the compound of formula (I), wherein: X is a single bond or a straight or branched chain, saturated or not, C1-C6, with one or more of the C atoms being optionally independently replaced with O or S , and wherein one or more of the H atoms are optionally replaced with F; Y is a single bond, CH (OH) -, or -C (O) -; R1 is H, alkyl, aryl, heteroaryl, cycloalkyl, or heterocycloalkyl; R2 is H, alkyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, or C (O) R 10; wherein R10 is H, alkyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, cycloalkyl, or heterocycloalkyl; and R12 is H, alkyl, aryl, heteroaryl, cycloalkyl, or heterocycloalkyl; or R11 and R12 form, together with the Nal to which they are attached, a heteroaryl or heterocycloalkyl; R3 is H, alkyl, aryl, heteroaryl, cycloalkyl, heterocycloalkyl, NR11R12 or OR11, where R11 and R12 have the meaning already given; or R2 and R3, together with the atom (s) to which / to which they are attached, form cycloalkyl or heterocycloalkyl; R4 is H or a suitable organic half; R5 is C (O) NHOH, C (O) OR13, SH, N (OH) CHO, SC (O) R14, P (O) (OH) R15 or P (O) (OH) R25 OP (O) ( OH) OR13; R13 is H, alkyl or aryl; R14 is alkyl or aryl and R 15 is alkyl; (2) y is heteroaryl with five ring atoms, including 1, 2 or 3 heteroatoms chosen from O, S and N; or a pharmaceutically acceptable salvate thereof, or a pharmaceutically acceptable prodrug thereof, said prodrug being different from a compound of formula (I); with the proviso that if the compound of formula (I) is: where R1, R4 and R5 have the meanings already given, W is H, OH, haloalkyl or O-alkyl, and furthermore: when it is 2, 3 or 4; n e s 1, 2, 3 or 4; and A is CH2, O, NH or N-alkyl; or when m is 4, 5 or 6; n is = and A is-CHJ-, where J |