http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-008593-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17 |
| filingDate | 1997-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2000-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-008593-A1 |
| titleOfInvention | A COMPOUND TO BE USED IN THE PREPARATION OF A MEDICATION TO INHIBIT THE IMPDH ACTIVITY, A PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT AND A METHOD TO TREAT OR PREVENT AN IMPDH MEDIATED DISEASE WITH SUCH COMPOSITION. |
| abstract | A compound to be used in the preparation of a medicament to inhibit IMPDH activity, characterized in that the compound has the formula I where: A is selected from: a straight or branched (C1-C6) alkyl, or a straight alkenyl or alkynyl or branched (C2-C6); and A optionally comprises up to 2 substituents wherein: the first of said substituents, if present, is selected from R1 or R3, and the second of said substituents, if present is R1; B is a saturated, unsaturated or partially saturated bicyclic or monosyclic ring system optionally comprising 4 heteroatoms selected from the formulas where each of x is the number of hydrogen atoms necessary to complete the appropriate valence, and B optionally comprises 3 substituents, where : the first of said substituents, if present, is selected from R1, R2, R4 or R5, the second of said substituents, if present is selected from R1 or R4, and the third of said substituents, if present, is R1 ; and D is selected from C (O), C (S), O S (O), wherein: each R1 is independently selected from 1,2-methylenedioxy, 1,2-ethylenedioxy, R6 or (CH2) n-Y; where n is 1 or 2; and Y is selected from halogens, CN, NO2, CF3, OCF3, OH, SR6, S (O) R6, SO2R6, NH2, NHR6, N (R6) 2, NR6R8, COOH, COOR6 or OR6, each R2 is independently selected from alkyl straight or branched (C1-C4) or a straight or branched alkenyl or alkynyl (C2-C4); and each R2 optionally comprises up to 2 substituent s where: the first of said substituents, if present, is R1; R3 is selected from an obicyclic monocyclic ring system consisting of 5 to 6 members per ring wherein said ring system optionally comprises 4 heteroatoms selected from N, O, or S, Y |
| priorityDate | 1996-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458392451 |
Total number of triples: 41.