| abstract |
Derivatives of piperidine and pyrrolidine of formula (I), where: R1 is unsubstituted phenyl, or mono-, di or trisubstituted with A, AO-, Hal, CN, NO2, NH2, Ph, -O-SO2A and / or -O-SO2CF3, 2- or 3-indolyl unsubstituted, either mono or disubstituted with A, AO-, OH, Hal and / or CN, 1,4-benzodioxan-5- or 6-yl, or1- or 2-naphthyl; R2 is unsubstituted phenyl or pyridyl, either mono or disubstituted with A, A-O, OH, Hal and / or CN; R3 is H, A, A-O-, Ph, NHR4 or NR5R6: k, l are independently 0 or 1; m is 0, 1 or 2 and n is 1 or 2 or their salts and intermediates. It also refers to a process for preparing these compounds and their physiologically acceptable salts, pharmaceutical preparations containing them and the use of them to combat eating disorders, learning disorders, age-dependent memory disorders. , dyskinesia, and to exert a positive influence on behavior in stressful situations. The compounds of formula (I) exhibit a 5-HT1A receptor antagonist action and inhibit 5-HT reuptake. These compounds can be used to prepare medicines. |