http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-005864-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-34 |
| filingDate | 1996-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1999-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-005864-A1 |
| titleOfInvention | DERIVATIVES OF CAFALOSPORIN, ITS EMPLOYMENT, PROCEDURE TO PREPARE THEM, A PHARMACEUTICAL PREPARATION CONTAINING SUCH A DERIVATIVE AND USEFUL COMPOUNDS TO PREPARE SUCH DERIVATIVES. |
| abstract | Cephalosporin derivatives of the general formula (I), wherein: R1 is a group chosen from 2-, 3- and 4-hydroxyphenyl, 2- and 3-methoxyphenyl, 4-carboxyphenyl, 4-carbamoylphenyl, 3-trifluoromethylphenyl, 2 - and 3-fluoro-phenyl, 3-nitrophenyl, 3-fluoro-4-hydroxyphenyl, 2-fluoro-4-hydroxyphenyl, 3-fluoro-2-hydroxyphenyl, 3-, 4-dihydroxy-phenyl, benzyl, -CHR- phenyl, 3-hydroxybenzyl, 4-amino-benzyl, 2-, 3- and 4-fluorobenzyl, 2-, 3- and 4-methoxybenzyl, 4-nitrobenzyl, 4-carboxybenzyl, 4-trifluoromethylbenzyl, 1-naphthyl and 2 -naphthyl, with all hydroxyl, amino, carboxyl and carbamoyl substituents being optionally substituted, or is mono-substituted halogen-pyridinyl, lower alkyl-substituted di-pyrinyl, mono-halogen-substituted pyridinyl, piperidinyl where the amino group may be substituted by an acyl group, thiadiazolyl, oxotetrahydrofuranyl, thiophenylomono-substituted by lower alkoxycarbonyl or carbamoyl, tetrazolyl-lower alkyl, tetrahydr ofuranyl-lower alkyl, thiophenyl-lower alkyl obenzimidazolyl-lower alkyl; and R is carboxyl or esterified carboxyl; their easily hydrolyzable esters, pharmaceutically acceptable salts of said derivatives and hydrates of the derivatives of formula (I) and their esters and salts, as well as their use, the process for the preparation of these derivatives, a pharmaceutical preparation containing such a derivative and useful compounds to prepare said derivatives. |
| priorityDate | 1995-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.