http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-005454-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D507-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D507-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D507-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-00 |
filingDate | 1997-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-005454-A1 |
titleOfInvention | DERIVATIVES OF ISOOXACEFEM, ITS USE, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING SUCH DERIVATIVES. |
abstract | Isooxacefem derivatives of the general formula (I) wherein R1 is hydrogen or an acyl group derived from a carboxylic acid; R2 is hydrogen, hydroxy, lower alkyl, cycloalkyl, lower alkoxy, lower alkenyl, cycloalkenyl, lower quinyl, aryl-lower alkyl, aryl, aryloxyaryl-lower alkoxy or a heterocyclic ring, the lower alkyl being cycloalkyl, lower aalkoxy, alkenyl lower, cycloalkenyl, lower alkynyl, aryl-lower alkyl, aryl, aryloxy, aryl-lower alkoxy and the heterocyclic ring unsubstituted or substituted with at least one group selected from carboxy, amino, nitro, cyano, lower alkyl, lower alkoxy, hydroxy , halogen, -CONR21R22, -N (R22) COOR 23, R22CO-R22OCO- or R22COO- wherein R21 is hydrogen, lower alkyl, or cycloalkyl; R22 is hydrogen or lower alkyl; R23 is lower alkyl, lower alkenyl, or a carboxylic acid protecting group; as well as easily hydrolyzable esters thereof, pharmaceutically acceptable salts of said derivatives and hydrates of derivatives of formula I and of their esters and salts. The invention further relates to the use of said derivatives, to a process for their preparation and to pharmaceutical preparations containing said derivatives. |
priorityDate | 1996-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.