| abstract |
The present invention relates to a process for the preparation of the compound D-tartrate of (-) - cis-6- (S) -phenyl-5 (R) - [4- (2-pyrrolidin-1-ylethoxy) phenyl] - 5,6,7,8-tetrahydronaphthalen-2-ol, comprising: a) dissolving cis-6-phenyl -5- [4- (2-pyrrolidin-1-ylethoxy) phenyl] -5,6,7,8 -tetrahydronaphthalene-2-ol racemic, or partially optically enriched, in boiling aqueous ethanol to form a solution; b) adding to said solution an equal molar amount of D-tartaric acid dissolved in aqueous l to form a second solution; c) cooling said second solution; and d) collecting the product formed in step c). |