| abstract |
These are microsomal triglyceride transfer protein inhibitors that respond to formulas (I), where X is a group CHR8, (II); R8, R9 and R10 are independently alkyl, saturated or not, aryl, arylalkyl, het-eroaryl , heteroarylalkyl, cycloalkyl or cycloalkylalkyl, R1 is a group of the fluorenyl or indenyl type which may have heterocycles of 5 to 6 condensed elements and their corresponding n-oxides and Q is a group -CO- or-SO2. A procedure is also proposed to prepare said inhibitors and intermediates for their synthesis. |