| abstract |
The invention provides S-(-r)-3-{l-(l,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl}-l-methyI-lH-indole-6-carboxylic acid, which is substantially free from its (R)-(-)-enantiomer, and, pharmaceutically acceptable derivatives thereof. The compounds are useful in the treatment of inter alia acute renal failure, restenosis and pulmonary hypertension. |