| abstract |
A method of preparation for the compound (-) cls-S(S)-phenyl-5(R)-[4-(2- pyrrolidin-1-yl ethoxy) phenylj-5,6,7,8-tetrahyaronaphthalen-2-ol D-tartrate which comprises: a) dissolving racemic or partially optically enriched cis-5-phenyi-5-[4-(2- pyrrolidin-1-yl ethoxy) phenyl]-5,6,7,3-tetrahydronaphtrv=ien-2-ol in boiling aqueous ethanol to form a solution; b) adding an equal molar amount of D-tartaric acid dissolved in aqueous ethanol to said solution to form a second solution; c) cooling said second solution; and d) collecting the product formed in step C |