title |
HMG-CoA Reductase Enzyme Assay and Inhibition of Cellular Cholesterol Synthesis Assay from Article 10.1021/jm070849r: \"Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.\" |