title |
Induction of read through activity at premature termination codon TAA (non-sense mutation associated with DMD disease) in 27-mer DNA stretch sequence of mouse dystrophin mdx gene transfected as a plasmid by connecting with beta-galactosidase and luciferase genes in COS7 cells assessed as ratio of luciferase activity to beta-galactosidase activity at 200 uM incubated for 48 hrs by dual luciferase reporter gene assay relative to control |