title |
Ratio of inhibition of P-gp overexpressed in human DU145-TxR cells assessed as increase in intracellular compound accumulation after 2.5 hrs in presence of tariquidar by LC-MS/MS analysis to Inhibition of P-gp overexpressed in human DU145-TxR cells assessed as decrease in intracellular compound accumulation after 2.5 hrs in absence of tariquidar by LC-MS/MS analysis |