title |
Inhibition of amyloid beta (1 to 42)-induced mPTP opening in mouse HT22 cells assessed as reduction in mitochondrial membrane potential loss by measuring green to red fluorescence ratio at 5 uM preincubated for 10 mins followed by amyloid beta (1 to 42) addition and measured every 1 hr for 3 hrs by JC1 staining based fluorescence assay relative to control |