http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID438951

Outgoing Links

Predicate Object
abstract F-box domain found in F-box/LRR-repeat protein 10 (FBXL10) and similar proteins. FBXL10 is also called lysine-specific demethylase 2B (KDM2B), CXXC-type zinc finger protein 2 (CXXC2), F-box and leucine-rich repeat protein 10, F-box protein FBL10, JmjC domain-containing histone demethylation protein 1B (JHDM1B), Jumonji domain-containing EMSY-interactor methyltransferase motif protein, protein JEMMA, protein-containing CXXC domain 2, [Histone-H3]-lysine-36 demethylase 1B, or NDY1. It is a histone demethylase that catalyzes the demethylation of H3K4me3 and H3K36me2, thereby playing a central role in the histone code. It preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. FBXL10 may also serve as the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.
title F-box_FBXL10
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32404043
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18013136
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8778113
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/482193
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24993794
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30334338
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3921839
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6013424
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6694189
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29520631
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7430057
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9413513
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29729267
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11395063
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30357187
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1211599
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2709582
http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11498496
type http://purl.obolibrary.org/obo/SO_0000417

Incoming Links

Predicate Subject
has component http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6P1G2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8NHM5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ640I9

Total number of triples: 24.