http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID410548
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | second Tudor domain found in SET domain bifurcated 1 (SETDB1) and similar proteins. SETDB1, also called ERG-associated protein with SET domain (ESET), histone H3-K9 methyltransferase 4, H3-K9-HMTase 4, or lysine N-methyltransferase 1E (KMT1E), acts as a histone-lysine N-methyltransferase that specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). It mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. It contains two Tudor domains. This model corresponds to the second one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions. |
| title | Tudor_SETDB1_rpt2 |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18033026 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30137860 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/19366255 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9876061 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2279576 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/33540240 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/33009468 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20896418 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9146100 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 16.