http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID410394
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | second protein kinase C conserved region 1 (C1 domain) found in protein kinase D3 (PKD3) and similar proteins. PKD3 is also called PRKD3, PRKCN, serine/threonine-protein kinase D3 (nPKC-D3), protein kinase C nu type (nPKC-nu), or protein kinase EPK2. It converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. It is involved in the regulation of the cell cycle by modulating microtubule nucleation and dynamics. PKD3 acts as a key mediator in several cancer development signaling pathways. PKD3 contains N-terminal tandem cysteine-rich zinc binding C1 (PKC conserved region 1), central PH (Pleckstrin Homology), and C-terminal catalytic kinase domains. This model corresponds to the second C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites. |
| title | C1_PKD3_rpt2 |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24775457 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26166222 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18774384 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/14192170 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/12829750 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1122499 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/19453437 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6667774 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29475136 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17347202 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/14038466 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/28700760 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3934348 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29478064 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24987471 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
| Predicate | Subject |
|---|---|
| has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO94806 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_005804 |
Total number of triples: 20.