conserveddomain/PSSMID410049

Predicate	Object
abstract	RNA recognition motif (RRM) found in pre-mRNA cleavage factor Im 59 kDa subunit (CFIm59 or CPSF7) and similar proteins. This subgroup corresponds to the RRM of CFIm59. Cleavage factor Im (CFIm) is a highly conserved component of the eukaryotic mRNA 3' processing machinery that functions in UGUA-mediated poly(A) site recognition, the regulation of alternative poly(A) site selection, mRNA export, and mRNA splicing. It is a complex composed of a small 25 kDa (CFIm25) subunit and a larger 59/68/72 kDa subunit. The two separate genes, CPSF6 and CPSF7, code for two isoforms of the large subunit, CFIm68 and CFIm59. The family includes CFIm59, also termed cleavage and polyadenylation specificity factor subunit 6 (CPSF7), or cleavage and polyadenylation specificity factor 59 kDa subunit (CPSF59). CFIm59 contains an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), a central proline-rich region, and a C-terminal RS-like domain. The N-terminal RRM of CFIm59 mediates the interaction with CFIm25. It also serves to enhance RNA binding and facilitate RNA looping.
title	RRM_CFIm59
isDiscussedBy	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/31611895 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/22833269 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7282137 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7972876 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/434018
type	http://purl.obolibrary.org/obo/SO_0000417

Predicate	Subject
has component	http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8N684 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8BTV2 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5XI29

Total number of triples: 11.