http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID409449
Outgoing Links
Predicate | Object |
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abstract | Immunoglobulin (Ig)-like domain of vascular endothelial growth factor receptor 3 (VEGFR-3); member of the I-set of Ig superfamily (IgSF) domains. The members here are composed of the immunoglobulin (Ig)-like domain of vascular endothelial growth factor receptor 3 (VEGFR-3). The VEGFRs have an extracellular component with seven Ig-like domains, a transmembrane segment, and an intracellular tyrosine kinase domain interrupted by a kinase-insert domain. VEGFRs bind VEGFs with high affinity at the Ig-like domains. VEGFR-3 (Flt-4) binds two members of the VEGF family (VEGF-C and VEGF-D) and is involved in tumor angiogenesis and growth. This group belongs to the I-set of IgSF domains, having A-B-E-D strands in one beta-sheet and A'-G-F-C-C' in the other. Like the V-set Ig domains, members of the I-set have a discontinuous A strand, but lack a C" strand. |
title | IgI_VEGFR-3 |
isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/27419701 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9726963 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/5128789 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9726962 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20007679 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21894000 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9080750 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13851562 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15142594 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29507003 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/208670 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10586411 |
type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Predicate | Subject |
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has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_891555 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP35916 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCCAA49505 |
Total number of triples: 18.