http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID350459
Outgoing Links
Predicate | Object |
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abstract | catalytic domain of receptor-type tyrosine-protein phosphatase R. Receptor-type tyrosine-protein phosphatase-like R (PTPRR or R-PTP-R), also called protein-tyrosine phosphatase PCPTP1, belongs to the family of classical tyrosine-specific protein tyrosine phosphatases (PTPs). PTPs (EC 3.1.3.48) catalyze the dephosphorylation of phosphotyrosine peptides. PTPRR is a kinase interaction motif (KIM)-PTP, characterized by the presence of a 16-amino-acid KIM that binds specifically to members of the MAPK (mitogen-activated protein kinase) family. The human and mouse PTPRR gene produces multiple neuronal protein isoforms of varying sizes (in human, PTPPBS-alpha, beta, gamma and delta). All isoforms contain the KIM motif and the catalytic PTP domain. PTPRR-deficient mice show significant defects in fine motor coordination and balance skills that are reminiscent of a mild ataxia. |
title | R-PTPc-R |
isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24832123 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/12138379 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7198923 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11448060 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2704959 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16161969 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20094193 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/23590642 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/23620922 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/12490505 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/31501547 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3075180 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/27578903 |
type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Predicate | Subject |
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has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ15256 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_002840 |
Total number of triples: 18.