http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID349730
Outgoing Links
Predicate | Object |
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abstract | BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily G member 4 (KCNG4). KCNG4, also called voltage-gated potassium channel subunit Kv6.4, is a silent voltage-gated potassium (KvS) channel subunit that can form functional heterotetrameric channels with KCNB1 (also known as Kv2.1), and further modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1. Voltage-gated potassium (Kv) channels are composed of alpha subunits, which form the actual conductance pore, and cytoplasmic beta subunits, which are auxiliary proteins that associate with alpha subunits to modulate the activity of the Kv channel. KCNG4 is a regulatory alpha subunit that cannot form a functional homo-tetrameric channel. It forms hetero-tetrameric channels (with other functional alpha subunits) through its BTB/POZ domain, also known as tetramerization (T1) domain, which is a versatile protein-protein interaction motif. |
title | BTB_POZ_KCNG4 |
isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13463634 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32901994 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7935763 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8756531 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21300138 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8715083 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9431496 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30949206 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30295630 |
type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Predicate | Subject |
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has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8TDN1 |
Total number of triples: 13.