http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID349493
Outgoing Links
Predicate | Object |
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abstract | SWIB domain found in BRG1-associated factor 60A (BAF60A) and similar proteins. BAF60A, also termed SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1), or 60 kDa BRG-1/Brm-associated factor subunit A, or SWI/SNF complex 60 kDa subunit, is a core subunit of the SWI/SNF chromatin-remodeling complex that activates the transcription of fatty acid oxidation genes during fasting. BAF60A is involved in chromatin remodeling and hepatic lipid metabolism. It mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation. It is also a key component of the transcriptional control in cardiac progenitors. Moreover, BAF60A interacts with p53 to recruit the SWI/SNF complex, suggesting that the SWI/SNF chromatin remodeling complex is involved in the suppression of tumors. |
title | SWIB_BAF60A |
isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/514398 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/22627327 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20020040 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13349466 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/23445127 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2456820 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17410625 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24685141 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2696913 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13803557 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32081858 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15500374 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13990170 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17499505 |
type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Predicate | Subject |
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has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ96GM5 |
Total number of triples: 18.