http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID349283
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | chromodomain of M-phase phosphoprotein 8. The chromodomain of M-phase phosphoprotein 8 (MPP8), a component of the RanBPM-containing large protein complex, binds methylated H3K9. This may in turn recruit the H3K9 methyltransferases GLP and ESET, and DNA methyltransferase 3A to the promoter of the E-cadherin gene, mediating the E-cadherin gene silencing and promoting tumor cell motility and invasion. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. |
| title | CD_MMP8 |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/28911623 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16552062 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13864119 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24212162 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15833121 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6396050 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29385497 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9702287 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
| Predicate | Subject |
|---|---|
| has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACC3R93_A http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_059990 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACC3QO2_A |
Total number of triples: 14.