http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID270755
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | Catalytic domain of the Protein Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 3. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. SGK3 (also called cytokine-independent survival kinase or CISK) is expressed in most tissues and is most abundant in the embryo and adult heart and spleen. It was originally discovered in a screen for antiapoptotic genes. It phosphorylates and inhibits the proapoptotic proteins, Bad and FKHRL1. SGK3 also regulates many transporters, ion channels, and receptors. It plays a critical role in hair follicle morphogenesis and hair cycling. The SGK3 subfamily is part of a larger superfamily that includes the catalytic domains of other STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase. |
| title | STKc_SGK3 |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17316648 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/28802876 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13276458 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/22058049 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1020355 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15974778 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32756287 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26794692 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6498570 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18662441 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/31519212 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21995087 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/19389239 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26143282 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30856667 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
| Predicate | Subject |
|---|---|
| has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ96BR1 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_001028750 |
Total number of triples: 20.