http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID270754
Outgoing Links
Predicate | Object |
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abstract | Catalytic domain of the Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 2. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. SGK2 shows a more restricted distribution than SGK1 and is most abundantly expressed in epithelial tissues including kidney, liver, pancreas, and the choroid plexus of the brain. In vitro cellular assays show that SGK2 can stimulate the activity of ion channels, the glutamate transporter EEAT4, and the glutamate receptors, GluR6 and GLUR1. The SGK2 subfamily is part of a larger superfamily that includes the catalytic domains of other STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase. |
title | STKc_SGK2 |
isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21981131 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15225976 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32756287 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21995087 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20735740 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/14609819 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/31519212 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/5777197 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21978644 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9766283 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6498570 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/5729997 |
type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Predicate | Subject |
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has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_001186193 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9HBY8 |
Total number of triples: 17.