http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID239579
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this family reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Proteins in this subfamily are classified as Type C SQRs because they contain two transmembrane subunits and one heme group. The heme and quinone binding sites reside in the transmembrane subunits. The SdhC or CybL protein is one of the two transmembrane subunits of bacterial and eukaryotic SQRs. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the membrane anchor subunits via electron transport through FAD and three iron-sulfur centers. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes. |
| title | SQR_TypeC_SdhC |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/5654993 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13916506 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/25130740 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/19996990 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10556508 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20034060 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26797564 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2339218 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16542503 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3662188 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30756947 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30756946 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/29469625 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 24.