http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID239356
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | GST_N family, Class Tau subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress. The GST fold contains an N-terminal TRX-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. The plant-specific class Tau GST subfamily has undergone extensive gene duplication. The Arabidopsis and Oryza genomes contain 28 and 40 Tau GSTs, respectively. They are primarily responsible for herbicide detoxification together with class Phi GSTs, showing class specificity in substrate preference. Tau enzymes are highly efficient in detoxifying diphenylether and aryloxyphenoxypropionate herbicides. In addition, Tau GSTs play important roles in intracellular signalling, biosynthesis of anthocyanin, responses to soil stresses and responses to auxin and cytokinin hormones. |
| title | GST_N_Tau |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/4138348 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17204609 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9211564 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7878249 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32697413 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16385692 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11852337 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11190554 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15025696 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/25471838 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1652767 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32098823 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7781675 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13867245 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/33512112 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/243466 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32745344 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 47.