http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID239351
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | GST_N family, Class Phi subfamily; composed of plant-specific class Phi GSTs and related fungal and bacterial proteins. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress. The GST fold contains an N-terminal TRX-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. The class Phi GST subfamily has experience extensive gene duplication. The Arabidopsis and Oryza genomes contain 13 and 16 Phi GSTs, respectively. They are primarily responsible for herbicide detoxification together with class Tau GSTs, showing class specificity in substrate preference. Phi enzymes are highly reactive toward chloroacetanilide and thiocarbamate herbicides. Some Phi GSTs have other functions including transport of flavonoid pigments to the vacuole, shoot regeneration and GSH peroxidase activity. |
| title | GST_N_Phi |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24032944 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15166364 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9211564 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18587725 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26645958 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/310105 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17234831 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32745344 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/31346867 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3020084 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/30034910 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24774150 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/33512112 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13867245 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/14459153 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7781675 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15166374 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 26.