http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID238703
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span. CobB is a bacterial sirtuin that deacetylates acetyl-CoA synthetase at an active site lysine to stimulate its enzymatic activity. |
| title | SIRT5_Af1_CobB |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/5038578 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2952238 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 14.