http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID238040
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation. |
| title | FReD |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26719471 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15102191 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26719491 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26719531 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9738414 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2903835 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/13666019 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26677134 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 41.