http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID198451
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | Ligand Binding Domain of Ephrin type-A Receptor 5. Ephrin receptors (EphRs) comprise the largest subfamily of receptor tyrosine kinases (RTKs). Class EphA receptors bind GPI-anchored ephrin-A ligands. There are ten vertebrate EphA receptors (EphA1-10), which display promiscuous interactions with six ephrin-A ligands. EphA5 is almost exclusively expressed in the nervous system. EphRs contain a ligand binding domain and two fibronectin repeats extracellularly, a transmembrane segment, and a cytoplasmic tyrosine kinase domain. Binding of the ephrin ligand to EphR requires cell-cell contact since both are anchored to the plasma membrane. The resulting downstream signals occur bidirectionally in both EphR-expressing cells (forward signaling) and ephrin-expressing cells (reverse signaling). |
| title | EphR_LBD_A5 |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/22789624 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/4976241 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/26889068 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9257458 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/5040448 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/4976240 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18033092 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2425156 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32199004 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2438219 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
| Predicate | Subject |
|---|---|
| has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP54756 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_004430 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCNP_872272 |
Total number of triples: 16.