http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID143593
Outgoing Links
Predicate | Object |
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abstract | N-carbamyl-D-amino acid amidohydrolase (DCase, class 6 nitrilases). DCase hydrolyses N-carbamyl-D-amino acids to produce D-amino acids. It is an important biocatalyst in the pharmaceutical industry, producing useful D-amino acids for example in the preparation of beta-lactam antibiotics. This subgroup belongs to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 6. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. Agrobacterium radiobacter DCase forms a tetramer (dimer of dimers). Some DCases may form trimers. |
title | DCase |
isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32694601 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/260035 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/3627118 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15840614 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10463079 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/25381342 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/156383 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/2965889 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11127879 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/374784 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/1680703 |
type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Predicate | Subject |
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has component | http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5S260 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ44185 http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP60327 |
Total number of triples: 17.