http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID143450
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins. NAD(P)+-dependent, aldehyde dehydrogenase, family 3 members A1 and B1 (ALDH3A1, ALDH3B1, EC=1.2.1.5) and fatty aldehyde dehydrogenase, family 3 member A2 (ALDH3A2, EC=1.2.1.3), and similar sequences are included in this CD. Human ALDH3A1 is a homodimer with a critical role in cellular defense against oxidative stress; it catalyzes the oxidation of various cellular membrane lipid-derived aldehydes. Corneal crystalline ALDH3A1 protects the cornea and underlying lens against UV-induced oxidative stress. Human ALDH3A2, a microsomal homodimer, catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Human ALDH3B1 is highly expressed in the kidney and liver and catalyzes the oxidation of various medium- and long-chain saturated and unsaturated aliphatic aldehydes. |
| title | ALDH_F3AB |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11782231 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/6528473 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20634723 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 20.