http://rdf.ncbi.nlm.nih.gov/pubchem/conserveddomain/PSSMID100095
Outgoing Links
| Predicate | Object |
|---|---|
| abstract | GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of UDP-N-acetylglucosamine, an essential precursor to components of the cell envelope. In order to be active, GlmM must be phosphorylated, which can occur via autophosphorylation or by the Ser/Thr kinase StkP. GlmM functions in a classical ping-pong bi-bi mechanism with glucosamine-1,6-diphosphate as an intermediate. Other members of the alpha-D-phosphohexomutase superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model. |
| title | GlmM |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21277436 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7072468 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20634890 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/7746446 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/20689754 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15171682 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21346119 http://rdf.ncbi.nlm.nih.gov/pubchem/reference/28700583 |
| type | http://purl.obolibrary.org/obo/SO_0000417 |
Incoming Links
Total number of triples: 393.