http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_ff1555bcef0ea6655ffda05219b6536c
Outgoing Links
Predicate | Object |
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family-name | H. Zhang Zhang |
name | H. Zhang H Zhang |
given-name | H H. |
organization-name | Department of Abdominal Surgery, Cancer Hospital, National Laboratory of Molecular Oncology, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, 100021 China. Brookdale Center for Molecular Biology, Mount Sinai School of Medicine, New York 10029, USA. State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi International Joint Research Center for Oral Diseases Department of Oral Anatomy and Physiology and TMD School of Stomatology The Fourth Military Medical University Xi'an China State Key Laboratory of Rice Biology, Key Laboratory of Molecular Biology of Crop Pathogens and Insects Ministry of Agriculture Hangzhou Zhejiang China Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Key Laboratory of Reproduction and Genetics in Ningxia; Department of Histology and Embryology, Ningxia Medical University; Tissue Organ Bank and Tissue Engineering Centre, General Hospital of Ningxia Medical University, Ningxia, China. Hepatobiliary Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. The International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai China Division of Reproduction and Endocrinology, Department of Physiology, Harbin Medical University, Harbin 150086, China. Emergency and Intensive Care Center, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Department of Laboratory Diagnosis, Changzheng Hospital, Second Military Medical University, Shanghai, China Department of Medicine, State University of New York Health Science Center at Syracuse 13210, USA. The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei‐MOST) & Key Laboratory of Oral Biomedicine Ministry of Education School and Hospital of Stomatology Wuhan University Wuhan China; Department of Periodontology, School and Hospital of Stomatology Wuhan University Wuhan China PUMC Hospital, CAMS and PUMC, Beijing. Biological Physics Group School of Physics & Astronomy The University of Manchester Manchester UK Center for Musculoskeletal Research, Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA State Key Laboratory of Food Science and Technology Jiangnan University Wuxi, Jiangsu China; School of Food Science and Technology Jiangnan University Wuxi, Jiangsu China; National Engineering Research Center for Functional Food Jiangnan University Wuxi, Jiangsu China; Wuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch Wuxi, Jiangsu China Department of Hand Surgery, People's Hospital of Jiangsu Province (the First Affiliated Hospital of Nanjing Medical University), Nanjing 210029, China. National Research Institute for Family Planning Beijing China; National Human Genetic Resources Centre Beijing China Xinghua Traditional Chinese Hospital, Xinghua, China Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University; and Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, PR China, Sports Medicine Service, Beijing Jishuitan Hospital, Beijing 100035, China. Department of Physiology, Shanxi Medical College, Taiyuan, China. Qinghai Provincial People's Hospital, Xining 810007. State Key Laboratory of Military Stomatology, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, Fourth Military Medical University, Xi’an, China Department of Plant and Soil Sciences Department of Epidemiology School of Public Health Tianjin Medical University Tianjin China Department of Cell Biology, Jiangsu Key Laboratory of Stem Cell Research, Medical College of Soochow University, Ren Ai Road, Suzhou Industrial Park, Suzhou, China Department of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China Department of Biology, Indiana University, Bloomington 47405, USA. Department of Nephrology and Rheumatology, Third Xiangya Hospital, Central South University,Changsha,China Department of Neurology, University of Maryland School of Medicine, Baltimore 21201. Beijing Ditan Hospital Capital Medical University Beijing China; Peking University People's Hospital Peking University Hepatology Institute Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases Beijing China Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI, USA Dorrance H. Hamilton Laboratories, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107. National University of Defense Technology College of Optoelectronic Science and Engineering, , Changsha 410073, People's Republic of China SmithKline Beecham Pharmaceuticals, Department of Cardiovascular Pharmacology, King of Prussia, Pa 19406. Xeotron Corporation, Houston, Texas 77054 Department of Gerontology, Shanghai East Hospital, Tongji University, Shanghai, China Department of Orthopaedic Surgery, Friendship Hospital, Capital University of Medical Sciences, Beijing. Key Laboratory of Systems Microbial Biotechnology; Tianjin Institute of Industrial Biotechnology; Chinese Academy of Sciences; Tianjin China School of Environmental Sciences, Univ. of Guelph Guelph ON Canada N1G 2W1 Center for Infectious Diseases Beijing YouAn Hospital Capital Medical University Beijing China Guangzhou Hospital of TCM. Institute of Cardiovascular Sciences University of Manchester Manchester UK Xiyuan Hospital, China Academy of TCM, Beijing 100091. Asthma Center, Gansu Provincial Hospital, Lanzhou 730000, China. Department of Biostatistics and Records Room, Medical Quality Management Office, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China Department of Hepatology, MAFLD Research Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. 159th Hospital of People's Liberation Army, Zhumadian, Henan. Department of Pediatric Hepatology, 302nd Hospital of PLA, Beijing 10003, China. Natural Medicine Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China The School of Nursing, Chengdu University of T.C.M., Chengdu 610075, China Radiology Department, Shanghai Jiaotong University affiliated First People's Hospital; Shanghai, China; University Medical Center Groningen; Groningen, the Netherlands Division of Epidemiology, Biostatistics and Environmental Health School of Public Health University of Memphis Memphis TN USA Affiliated Hospital of Guangzhou College of TCM. Department of Respiratory and Critical Care Medicine, Rizhao Hospital of Traditional Chinese Medicine, Rizhao 276800, China. Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, P. R. China Institute of Medicinal Bioechnology, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050. Department of Pathology, Qilu Hospital of Shandong University, Jinan 250012, China. Department of Endocrinology Shandong Provincial Hospital Affiliated to Shandong University Jinan Shandong China; Shandong Clinical Medical Center of Endocrinology and Metabolism Jinan Shandong China; Institute of Endocrinology and Metabolism Shandong Academy of Clinical Medicine Jinan Shandong China Nanjing University School of Medicine, Research Institute of Nephrology, Jingling Hospital, Nanjing, China Division of Immunology and Cancer Research, Hospital for Sick Children, Toronto, Canada. Department of Intensive Care, Erasme University Hospital, Faculty ofMedicine, Free University of Brussels, Belgium. University of Manchester 1 Biological Physics, , Manchester M13 9PL, United Kingdom Children’s Hospital of Philadelphia, Philadelphia, PA, USA; University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, P. R. China Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, National Children's Medical Center, Shanghai 200127, China. Department of AIDS Prevention and Control, Fuzhou City Center for Disease Control and Prevention, Fuzhou 350004, China School of Public Health,Fujian Medical University,Fuzhou 350122, China. Department of Biochemical Engeering, East China University of Science & Technology, Shanghai 200237. School of Environmental Sciences, Univ. of Guelph; Guelph ON Canada N1G 2W1 University of Pennsylvania School of Medicine, Philadelphia, PA, USA Beijing Laboratory for Food Quality and Safety, and Key Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, P.O. Box 303, No. 17 Tsinghua East Road, Beijing 100083, China P.R. Shandong Cancer Institute, Jinan. Laboratory for Physical Chemistry, University of Amsterdam, Nieuwe Achtergracht 129, 1018 WS Amsterdam, The Netherlands College of Veterinary Medicine Northwest A&F University Yangling Shaanxi Province China Clinical Laboratory of BGI Health; Shenzhen China Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei The Dorrance H. Hamilton Laboratories, Center for Human Virology, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. TAE Technologies, Inc. , Foothill Ranch, California 92610, USA Beijing University of Traditional Chinese Medicine. Department of Pathology, Sun yat-sen University of Medical Sciences Cancer Center, Guangzhou. Collaborative Innovation Center of Forest Resources Breeding and Utilization in Yunnan Kunming People's Republic of China Center for Clinical Epidemiological Research, Peking University Third Hospital, Beijing 100191, China. Department of Public Health, Shandong Medical University, Jinan, China. Department of Medical Genetics, University of British Columbia, Vancouver, Canada. Department of Intensive Care, Erasme University Hospital, FreeUniversity of Brussels, Belgium. Department of Gynecology, University Medical Hospital Benjamin Franklin, Free University Berlin, Germany. State Key Laboratory of Food Science and Technology; Jiangnan University; Wuxi Jiangsu China; School of Food Science and Technology; Jiangnan University; Wuxi Jiangsu China; National Engineering Research Center for Functional Food; Jiangnan University; Wuxi Jiangsu China Department of Pharmacology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, U.S.A. Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, Heilongjiang, P.R. China; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, Heilongjiang, P.R. China; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, Heilongjiang, P.R. China The Key Laboratory of Biomedical Information Engineering of the Ministry of Education of China, Institute of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, PR China. maxr@263.net State Key Laboratory of Food Science and Technology; School of Food Science and Technology; Jiangnan University; Wuxi Jiangsu China College of Public Health, Henan Medical University, Zhengzhou, China. Department of Othopedics, General Hostipal of Chinese People's Liberation Army, Beijing 100853. Laboratory of Seed Science and Technology State Key Laboratory of Crop Genetics and Germplasm Enhancement Jiangsu Collaborative Innovation Center for Modern Crop Production Nanjing Agricultural University Nanjing China Department of Biochemistry and Molecular Biology, Medical College of Shantou University, Shantou, Guangdong Province, PR China. Department of Urology; Medical Center for Overseas Patients; Nanfang Hospital of Southern Medical University; Guangzhou China Departments of Microbiology and Pediatric Dentistry, Schools of Dentistry and Medicine, University of Alabama at Birmingham, Birmingham, AL, USA Department of Obstetrics and Gynecology International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiaotong University Shanghai China; Institute of Embryo‐Fetal Original Adult Disease Affiliated to School of Medicine Shanghai Jiaotong University Shanghai China Department of Cardiac Surgery, Beijing Anzhen Hospital Capital Medical University Beijing China Department of Chemistry; Brandeis University; Waltham; USA Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University , Beijing, China; Beijing Lab for Cardiovascular Precision Medicine , Beijing, China Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia 19104-6059, USA. Department of General Surgery, Dongguan Kanghua Hospital, Dongguan, Guangdong 523080, China. Department of Oncology, Medical Centre of Zhuhai, Zhuhai 519000. From the Departments of Neurology (Drs. E.M. Frohman, Zhang, Hawker, Racke, and T.C. Frohman), Ophthalmology (Dr. E.M. Frohman), and Radiology (Dr. Fleckenstein), University of Texas Southwestern Medical Center, Dallas; and New Jersey Neuroscience Institute (Dr. Kramer), Seton Hall University, Edison, NJ. Fujian Institute of Research on the Structure of Matter , State Key Laboratory of Structural Chemistry, The Graduate School of the Chinese Academy of Sciences, Fuzhou, Fujian 350002, People’s Republic of China College of Biological Sciences, Beijing Agricultural University. Center for the Built Environment; University of California; Berkeley CA USA Tianjin Medical University Eye Hospital, Eye Institute and School of Optometry, Tianjin Branch of National Clinical Research Center for Ocular Disease, Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin 300384, China. Pediatric Endocrinology and Genetic, Xin Hua Hospital, Shanghai Institute for Pediatric Research, Shanghai Jiao Tong University School of Medicine Shanghai China Department of Epidemiology and Biostatistics Norman J. Arnold School of Public Health University of South Carolina Columbia SC USA Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS-Université , Bourgogne-Franche Comté, 9 Ave. A. Savary, BP 47 870, F-21078 Dijon Cedex, France Department of Pharmacology and Therapeutics, University of Melbourne, Parkville, VIC, Australia Department of Dermatology First Affiliated Hospital of Anhui Medical University Hefei China; Key Laboratory of Dermatology (Anhui Medical University) Ministry of Education Hefei China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Hefei China; Anhui Provincial Institute of Translational Medicine Hefei China Department of Entomology College of Plant Protection, Nanjing Agricultural University, Jiangsu/Key Laboratory of Monitoring and Management of Plant Diseases and Insects, Ministry of Agriculture Nanjing Jiangsu China Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie (IMPMC), Sorbonne Université, CNRS UMR 7590, IRD UMR 206, MNHN 1 , 4, Place Jussieu, Paris, France Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; Key Laboratory of Prevention and Control for Emerging Infectious Diseases of Guangdong Higher Institutes, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, China State Key Laboratory of Crop Stress Biology for Arid Areas, College of Agronomy, Northwest A&F University, Yangling, Shaanxi 712100, China Department of Epidemiology Center, Peking University Third Hospital, Beijing 100191, China. Department of Biological Sciences, Purdue University, West Lafayette, IN 47907; and Crop Biotechnology Center, Texas A&M University, College Station, TX 77843 Life Science College The Provincial Key Lab of the Conservation and Exploitation Research of Biological Resources in Anhui Anhui Normal University Wuhu Anhui China Science and Technology on Near-Surface Detection Laboratory 3 , Tonghuixi Road, Wuxi 214035, China Department of Pathology, Zhejiang Medical University, Hangzhou 310031. State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China Department of Ophthalmology, The Second Teaching Hospital, Tianjin Medical University, Tianjin 300211, China. Division of Epidemiology, Biostatistics and Environmental Health; School of Public Health; University of Memphis; Memphis TN USA Department of Physics and Astronomy, Michigan State University, East Lansing, MI, United States of America Environmental Engineering Research Centre, School of Civil and Structural Engineering Nanyang Technological University, Blk. N1, 50 Nanyang Avenue, Singapore 639798 Department of Child and Adolescent Health, Shandong University, Ji'nan 250012, China. Hainan Provincial Key Laboratory of Pests Detection and Control for Tropical Agriculture, Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, P.R. China Department of Clinical Laboratory No. 10 Hospital of Chinese People's Liberation Army Wuwei China Brookdale Center for Molecular Biology, Mt. Sinai School of Medicine, New York 10029-6574. Department of Respiratory Medicine, First Hospital of Beijing University, Beijing 100034, China. Division of Epidemiology Biostatistics and Environmental Health School of Public Health University of Memphis Memphis TN USA Renal Division, Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, and Key Laboratory of Chronic Kidney Disease Prevention and Treatment, Peking University, Ministry of Education, Beijing, China The University of Texas MD Anderson Cancer Center, USA Institute of Hydrobiology, Academia Sinica, Wuhan. Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University, Beijing 100026, China. School of Chemical Engineering, Shandong University of Technology, Zibo, 255049, P.R. China Anesthesiology, The Ohio State University, Columbus, Ohio 43210 Department of Otorhinolaryngology, The First Affiliated Hospital Xinjiang Medical University Urumqi China Affiliated Hospital of Shandong Medical University, Jinan. Department of Gastroenterology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. zhanghong671013@126.com First author: The Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, China; first, second, and fifth authors: Crop Diversification Centre North, Alberta Agriculture and Rural Development, Edmonton, AB, T5Y 6H3, Canada; and first, third, and fourth authors: Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, T6G 2P5, Canada. Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205. Division of Vascular Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China Department of Medical Sciences; Section of Dermatology; University Hospital; Uppsala Sweden National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China Renal Division, Peking University First Hospital, Peking University Institute of Nephrology, and Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, People's Republic of China College of Food Science Technology, Henan Agricultural University, Zhengzhou, China State Key Laboratory for Conservation and Utilization of Subtropical Agro‐Bioresources Guangxi University Nanning Guangxi China Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013. Food Science and Engineering College; Beijing University of Agriculture; Beijing Laboratory of Food Quality and Safety; Beijing Key Laboratory of Detection and Control of Spoilage Organisms and Pesticide Residues in Agricultural Products; Beijing China Department of Hematology, Affiliated Hospital of Jining Medical University, Jining 272000, China. State Key Laboratory of Integrated Management of Pest Insects and Rodents; Institute of Zoology; Chinese Academy of Sciences; Beijing 100101 China; State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of Zoology; Chinese Academy of Sciences; Beichenxilu 1-5 Beijing 100101 China Department of Neurology, Beijing Hospital. Dept. of Hepatology, First Hospital, Jilin University, Changchun 130021, China. Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Center of Dacryology, Second Affiliated Hospital, 1st Military Medical University, Guangzhou, China. Institute of Space Medico-Engineering, Beijing 100094, China. School of Physics and Electronic Technology, Liaoning Normal University 2 , Dalian 116029, China Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston 77555, USA. Beijing Respiratory Disease Research Center, Beijing Red Cross ChaoYang Hospital. Department of Critical Care Medicine, Peking Union Medical College Hospital, Beijing. Department of Integrated Chinese and Western Medicine Treatment Center Henan Cancer Hospital Zhengzhou China Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200011, China. Key Oasis Eco-Agriculture Laboratory of Xinjiang, Shihezi University, Shihezi 832003, PR China Department of Heavy Ion Radiation Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000, China; Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province, Lanzhou 730000, China Division of Epidemiology, Biostatistics, and Environmental Health School of Public Health, University of Memphis Memphis TN USA Department of Anethesiology, School of Stomatology, The Fourth Military Medical University & State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Xi'an 710032, China. Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Discipline of Pediatrics (Capital Medical University) ; Key Laboratory of Major Diseases in Children, Ministry of Education; Hematology Oncology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China(Zhang Han is working on the Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China). Affiliated Hospital of Shandong Medical University, Jian. Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, People's Republic of China College of Forestry, Sichuan Agricultural University, Chengdu, Sichuan Province, 611130, Sichuan, P.R. China Cytogenetics Institute, Nanjing Agricultural University, China. Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000. Department of Chemistry, Fuzhou University, 350002 Fuzhou. Division of Epidemiology, Biostatistics, and Environmental Health School of Public Health University of Memphis Memphis TN USA National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop Science Chinese Academy of Agricultural Sciences Beijing China First Central Clinical College of Tianjin Medical University, Tianjin 300192, China. Shanghai Institute of Materia Madica, Chinese Academy of Sciences. 302nd PLA Hospital Beijing China College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, P.R. China 210095 TZAM Diagnostics LLC, 1824 Wilmette Avenue, Wilmette, IL 60091, USA Anhui Provincial Engineering Technology Research Center of Biochemical Drugs, Bengbu 233030, China. Department of Obstetrics The First Affiliated Hospital of Chongqing Medical University Chongqing China; China‐Canada‐New Zealand Joint Laboratory of Maternal and Fetal Medicine Chongqing Medical University Chongqing China College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, Henan, China Janssen Research & Development LLC Spring House PA USA Laboratory of Molecular Biophysics, University of Alabama, Birmingham 35294. Yangzhou Manicipal Institute for Drug Control, Jiangsu. Department of Biochemical Engineering, East China University of Science and Technology, Shanghai 200237. Department of Colorectal Cancer, Shengjing Hospital, China Medical University, Shenyang 110004, China. Department of Environmental Science, IENS, Lancaster University, Lancaster, LA1 4YQ, UK, and School of Life and Environmental Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom Institute of Basic Medical Sciences, CAMS and PUMC, Beijing. Department of Radiotherapy; The First Affiliated Hospital of Nanjing Medical University; Nanjing Jiangsu China Department of Oncological Sciences, Huntsman Cancer Institute at the University of Utah, Salt Lake City 84112, USA. Jiangsu Engineering Technology Research Center of Mutton Sheep and Goat Industry, Nanjing Agricultural University, Nanjing 210095, P. R. China From the Department of Neurology (Dr. Shefner, T. Conrad, J. Taft, and M. Chilton), Upstate Medical University, Syracuse, NY; Department of Neurology (Dr. Cudkowicz, L. Urbinelli, and M. Qureshi) and Biostatistics Center (Dr. Schoenfeld and H. Zhang), Massachusetts General Hospital, Boston; Department of Neurology (Dr. Pestronk), Washington University, St. Louis, MO; Department of Neurology (Drs. Caress and Donofrio), Wake Forest University, Winston-Salem, NC; Department of Neurology (Dr. Sorenson),... Department of Pathology, Weinan Central Hospital, Shaanxi Province, Weinan 714000, China. Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020, China. Department of Urology Institute of Urology, West China Hospital, Sichuan University Chengdu China Institute of Geriatric & Gerontology, 301 Hospital, Beijing 100853, China. Institute of Fluid Physics, China Academy of Engineering Physics 1 , P.O. Box 919-106, Mianyang 621900, China; School of Physics, Peking University 2 , Beijing 100871, China Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021, China. Changsha University of Science and Technology School of Physics and Electronic Science, , Changsha 410004, People’s Republic of China School of Chemistry and Chemical Engineering; Harbin Institute of Technology; Harbin; China Qilu Hospital of Shandong University, 107 Wenhua W Road, Jinan, Shandong 250012, China. College of Life Science Qufu Normal University Jingxuan West Road No. 57 Qufu Shandong 273165 China Department of Immunogenetics, Beijing Children's Hospital, Beijing, 100045 P. R. China. Huiliz@netscape.net Department of Oncology The Second Xiangya Hospital Central South University Changsha China Shanghai Jiao Tong University. Department of Allergy, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China Department of Otolaryngology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China. Center for Advanced Biotechnology and Medicine, Piscataway, NJ 08854, USA. School of Pharmacy, West China University of Medical Sciences, Chengdu. Department of Radiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Centre for Precision Technologies, School of Computing and Engineering, University of Huddersfield, Huddersfield, UK Linkoping University, Sweden Centre of Dacryology, Zhujiang Hospital, First Military Medical University, Guangzhou, China. Department of Oncology & Immunotherapy Hebei General Hospital Shijiazhuang Hebei China National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing Phase 1 Clinical Unit, China‐Frontage USA, First Hospital Jilin University Changchun Jilin China PUMC Hospital, Beijing. Beijing College of Traditional Chinese Medicine. Department of Urology; Shandong Provincial Hospital Affiliated to Shandong University; Jinan Shandong China a State Key Laboratory of Tribology, School of Mechanical Engineering, Tsinghua University, Beijing 100084, P. R. China; Centre for Precision Technologies, School of Computing and Engineering, University of Huddersfield, Huddersfield HD1 3DH, UK. zhanghyu@tsinghua.edu.cn Department of Ophthalmology, The Second Teaching Hospital, Tianjin Medical University, Tianjin 300211. Division of Pharmacology, College of Pharmacy, Ohio State University, Columbus 43210. State Key Laboratory of Agricultural Microbiology; Huazhong Agricultural University; Wuhan Hubei China; College of Life Science and Technology; Huazhong Agricultural University; Wuhan Hubei China Urology Department First Affiliated Hospital of Xinxiang Medical College Xinxiang China Fujian Institute of Research on the Structure of Matter State Key Laboratory of Structural Chemistry, , The Chinese Academy of Sciences, Fuzhou 350002, People’s Republic of China Biomaterials and Engineering Center Wuhan University of Technology, PR China. zhhquan@yahoo.com Institute of Space Medico-Engineering, Beijing, China. General Hospital of People's Liberation Army. Fudan University, China Chinese Center for Disease Control and Prevention, Beijing, China; Department of Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, USA Graduate School of Dalian Medical University Dalian China Institute of Fluid Physics , CAEP, Mianyang 621900, China Department of Morphology, University of Geneva Medical School, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland Department of the Third General Surgery, Tianjin Xiqing Hospital, Tianjin, China Department of Epidemiology, Peking University Third Hospital, Beijing 100191, China. Department of Surgery, University of Chicago, Illinois 60637, USA Department of Pathology, Shanghai Sixth People's Hospital, Shanghai 200233, China. Department of Medicine, The University of Chicago, Illinois 06037,USA. Department of Pharmacognosy, Chengdu. Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China. School of Life and Environmental Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, U.K., Agriculture and Environment Division, IACR Rothamsted, Harpenden, Hertfordshire AL5 2JQ, U.K., Institute of Environmental and Biological Sciences, University of Lancaster, Lancaster LA1 4YQ, U.K., and Department of Plant and Soil Science, University of Aberdeen, Aberdeen AB24 3UU, U.K. Department of Biochemical Engineering, Zhejiang University, Hangzhou, China. Department of Thoracic Surgery, Shandong Province Chest Hospital, Jinan, P.R. China. tsmcyy@126.com. Department of Vaccine Engineering, Institute of Basic Medical Sciences, Beijing, China Institut d’Electronique Fondamentale, UMR 8622 CNRS, University Paris Sud XI, 91405 Orsay Cedex, France Department of Gynecology Tumor Hospital of Shaanxi Province Xi'an China Division of Respiratory Medicine, Mount Sinai Hospital, University of Toronto, Canada. haibo.zhang@utoronto.ca School of Public Health, Shanxi Medical University, Taiyuan, China. Research Center of Clinical Epidemiology,Peking University Third Hospital, Beijing 100191, China. Department of Occupational Disease Prophylactic-Therapeutic Institution, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu, China Colin Ratledge Center for Microbial Lipids; School of Agricultural Engineering and Food Science; Shandong University of Technology; Zibo China Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China. Thermo Fisher Scientific, BRIMS, (Biomarker research in Mass Spectrometry) Cambridge, Massachusettes, United States, Vast Scientific, Wayland, Massachusettes, United States, George Mason University, Fairfax, Virginia, United States, John Hopkins University, Baltimore, Maryland, United States, and Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada State Key Laboratory of Silkworm Genome Biology Southwest University Chongqing China Geological and Mining Engineering and Science Department; Michigan Technological University; Houghton; USA School of Nursing Nanjing University of Chinese Medicine Nanjing China Yanbian Medical College, Yanji. Department of Chemistry, Qufu Normal University, China. Department of Medicine, Toronto Hospital (Western Division), Canada. Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, Saskatoon, Canada; School of Life Science and Engineering, Foshan University, Foshan, China *John A. Moran Eye Center, University of Utah Health Science Center, Salt Lake City, UT 84132; BroadPharm, Inc., 9380 Waples Street, San Diego, CA 92121, USA Haikou Hospital of the Maternal and Child Health Hainan China State Key Laboratory of Food Science and Technology; Jiangnan University; Wuxi P. R. China; School of Food Science and Technology; Jiangnan University; Wuxi P. R. China State Key Laboratory of Food Science and Technology; Jiangnan University; Wuxi Jiangsu China; School of Food Science and Technology; Jiangnan University; Wuxi Jiangsu China; National Engineering Research Centre for Functional Food; Wuxi Jiangsu China Department of Chemistry, Kansas State University, Manhattan, Kansas 66502; Office of Biotechnology, Hybridoma Facilities, and Department of Chemistry, Iowa State University, Ames, Iowa 50011, and Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska 68198 Pennington Biomedical Research Center, Louisiana State University,Baton Rouge 70808-4124, USA. Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Anhui Province Key Laboratory of Major Autoimmune Diseases, Hefei 230032, China. Department of Hematology, Affiliated Hospital of Jining Medical University, Shangdong, Jining 272007,China. Department of Pathology, Xinjiang Medical University Cancer Hospital, Urumqi 830000, China. Department of Nephrology Taizhou Hospital of Zhejiang Taizhou, Zhejiang, China Department of Orthopedics, General Hospital of Chinese People's Liberation Army, Beijing 100853. Department of Microbial InspectionNanjing Municipal Center for Disease Control and Prevention Nanjing PR China Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China ARC Centre of Excellence for Electromaterials Science; Intelligent Polymer Research Institute; University of Wollongong; Wollongong, Australia Hubei College of Traditional Chinese Medicine, Wuhan. Metropolitan Water Reclamation District of Greater Chicago, 100 E. Erie St., Chicago, IL, 60611-2903, USA (E-mail: heng.zhang@mwrd.org; richard.lanyon@mwrd.org) Henan Key Laboratory of Ion Beam Bio‐engineering School of Agricultural Science Zhengzhou University Zhengzhou P. R. China; College of Food and Bioengineering Henan University of Animal Husbandry and Economy Zhengzhou P. R. China Department of Infectious Diseases and Medical Microbiology, Division of Investigative Science and Cell and Molecular Biology Section, Division of Biomedical Sciences, Imperial College School of Medicine, London, United Kingdom Stamotological Department, General Hospital of Beijing Military Area. Qinghai Provincial Key Laboratory of Crop Molecular Breeding, Xining 810008 China; University of Chinese Academy of Sciences, Beijing 100049, China; Key Laboratory of Adaptation and Evolution of Plateau Biota & Northwest Institute of Plateau Biology , Chinese Academy of Sciences, Xining 810008, China Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province; College of Animal Science and Technology, Northeast Agricultural University, Harbin, China *American Society of Human Genetics, Bethesda, MD 20814; Neurosurgery, The Second Affiliated hospital of Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China. Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, China. Intensive Care Unit, Nantong Hospital to Nanjing University of Chinese Medicine, Nantong, Jiangsu, China. Center for Reproductive Medicine; Provincial Hospital Affiliated to Shandong University; Jinan China Department of Dermatology Xinhua Hospital Shanghai Jiaotong University School of Medicine 1665 Kongjiang Road Shanghai 200092 China Department of Orthopaedics, General Hospital of Northern Theater Command, Shenyang, China Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences, and Key Laboratory of Monitoring and Control of Tropical Agricultural and Forest Invasive Alien Pests, Ministry of Agriculture, Haikou 571101, China Department of Emergency, Tianjin Children's Hospital,Tianjin 300074, China. Department of Endocrinology Shandong Provincial Hospital affiliated to Shandong University Jinan Shandong China; Institute of Endocrinology and Metabolism Shandong Academy of Clinical Medicine Jinan Shandong China; Shandong Clinical Medical Center of Endocrinology and Metabolism Jinan Shandong China Department of Neurology Changhai Hospital Shanghai Department of Biomedical Sciences, Texas A&M Baylor College of Dentistry, Dallas, TX, USA Department of Neurology,Qilu Hospital of Shandong University,Jinan 250012,China. Department of Otorhinolaryngology, Head and Neck Surgery, Xiangya Hospital, Central South University, Hunan Provincial Key Laboratory of Otorhinolaryngology Major Diseases, Changsha, 410008, China. Third Hospital of Wuxi, Wuxi 214041. Department of Epidemiology Sixth Hospital of Hangzhou Hangzhou China Changzhi Medical College, China School of Civil and Environmental Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798 (E-mail: chzhang@ntu.edu.sg; costab@ntu.edu.sg; cjhtay@ntu.edu.sg) Department of Gastroenterology, Wenzhou Central Hospital, Wenzhou 325000, China. Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing 100191, China. Department of Rheumatology and Immunology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital , 600 Yishan Road, Shanghai 200233, China From the Day Neuromuscular Research Laboratory, Department of Neurology (A.-M.W., J.E.L., R.H.B.), Biostatistics Center (H.Z.), and Neurology Clinical Trials Unit, Department of Neurology (A.J.C., M.E.C.), Massachusetts General Hospital, Harvard Medical School, Boston, MA; and Departments of Genome Sciences and Medicine (R.J.R., C.E.F.), Division of Medical Genetics, University of Washington, Seattle. Department of Dentistry, Central Hospital of Minhang District, Shanghai 201100, China. Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, WA, USA Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu Province, People's Republic of China Jiangsu Engineering Technology Research Center of Meat Sheep & Goat Industry Nanjing Agricultural University Nanjing China Department of Chemical and Materials Engineering, University of Alberta 2 , Edmonton, Alberta T6G 1H9, Canada Nagoya University 3 Department of Complex Systems Science, , Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan Department of Thoracic Surgery, Fourth Hospital, Hebei Medical University, Shijiazhuang 050011. The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei‐MOST) & Key Laboratory of Oral Biomedicine, Ministry of Education School and Hospital of Stomatology Wuhan University Wuhan Hubei China; Department of Periodontology School and Hospital of Stomatology Wuhan University Wuhan Hubei China Department of Thyroid Breast Surgery, Anhui Provincial Hospital, Hefei, Anhui, China. wangkang2136@163.com. School of Environmental Science; Nanjing Xiaozhuang University; Nanjing, 211171; P. R. China The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei‐MOST) & Key Laboratory of Oral Biomedicine Ministry of Education School & Hospital of Stomatology Wuhan University Wuhan China Department of Gastroenterology & Hepatology, Xijing Hospital, the 4th Military Medical University, Xi'an 710032, China. Rizhao Hospital of Traditional Chinese Medicine, Shandong 276800, China. Department of Dermatology Xinhua Hospital Shanghai Jiaotong University School of Medicine Shanghai China; Institute of Dermatology Shanghai Jiaotong University School of Medicine Shanghai China Laboratory for Experimental Brain Research University of Lund Lund Sweden Department of Pediatric Hepatic Disease, the 302nd Hospital of PLA, Beijing 100039, China. Beijing Tropical Medicine Research Institute, Beijing 100050. University of Toronto 9 Department of Physics, , Toronto, Ontario M5S 1A7, Canada Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013, China. Department of Radiology, Shanghai Jiaotong University Affiliated First People's Hospital; Shanghai, China Columbia University Irving Medical Center , New York, NY, USA Burn Unit, 159th Hospital, PLA, Zhumadian. Department of Plant Biology & Pathology The Rutgers Duckweed Stock Cooperative Rutgers, The State University of New Jersey New Brunswick NJ USA Department of Oncology Surgery, Fujian Provincial Hospital, Fuzhou 350001, China. Division of Biology, California Institute of Technology, Pasadena 91125. BGI Shenzhen Shenzhen China Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA. lebovitz@bcm.tmc.edu Regeneron Pharmaceuticals, Inc. Tarrytown NY USA First People's Hospital of Xiangtan, Hunan. Department of Prevention, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China. Department of Integrated Traditional Chinese and Western Medicine, Huashan Hospital, Fudan University, Shanghai, China Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai, China Department of Radiation Biology and Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, Gansu, People’s Republic of China; Corresponding authors with equal contribution Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs Institute of Animal Science Chinese Academy of Agricultural Sciences Beijing 100193 China; College of Life Science and Food Engineering Hebei University of Engineering Handan 056038 China Department of Radiation Oncology, Bowman Gray School of Medicine, Winston-Salem, NC 27157, USA. Membrane Science and Technology, Institute of Tianjin Polytechnic University, Tianjin 300160, China. Renal Division, Department of Medicine, Peking University First Hospital; Institute of Nephrology, Peking University; Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China Peking Union Medical College Hospital China Health Protection Agency, Clinical Microbiology and Public Health LaboratoryAddenbrooke’s Hospital, Box 236, Hills Road, Cambridge CB2 0QW, UK Department of Thoracic Surgery, Fourth Hospital, Hebei Medical University, Shijiazhuang. Department of Oral and Maxillofacial Surgery, College of Stomatology, Hebei Medical University & Key Laboratory of Stomatology, Shijiazhuang 050017, China. Center for Engineered Polymeric Materials; Department of Chemistry; College of Staten Island and Graduate Center of the City University of New York; Staten Island; USA Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China Department of Medicine, Monash University, Clayton, Australia. zhang.hua@med.monash.edu.au Organ Transplant Center; The First Affiliated Hospital of Sun Yat-Sen University; Guangzhou People's Republic of China Department of Pathology, Medical College, Jinan University, Guangzhou. University of California School of Medicine, Children,s Hospital Oakland Research Institute, Oakland, CA 94609, USA. Department of Surgery, University of Chicago, Illinois, USA. Department of Urology, Meizhou People's Hospital, Meizhou 514021, China. 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, The Key Laboratory of Hormones and Development (Ministry of Health), Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China Department of Biology Hong Kong Baptist University Waterloo Road Hong Kong China Department of Respiratory Diseases and Laboratory of Bacteriology, Shanghai Children's Hospital, Shanghai, China Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin, P. R. China State Key Laboratory of Biotherapy for Human Diseases, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, PR. China. Harris Birthright Research Centre for Fetal Medicine, Fetal Medicine Research Institute King's College Hospital London UK Research Center of Biological Therapy, Beijing 302 Hospital, Beijing Institute of Infectious Diseases, Beijing, China Department of Ophthalmology, First Teaching Hospital of Jining Medical College, Shandong Province, Jining 272111. State Key Laboratory of Food Science and Technology Jiangnan University Wuxi China; School of Food Science and Technology Jiangnan University Wuxi China; National Engineering Research Center for Functional Food Jiangnan University Wuxi China West China School of Preclinical and Forensic Medicine, Sichuan University 1 , Chengdu610041, Sichuan, P. R. China .; Center of Forensic Sciences, Bureau of Public Security of Sichuan Province 2 , Chengdu610041, Sichuan, P. R. China . Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China. Graduate School, Southern Medical University, Guangzhou 510515, China; Department of Joint Surgery, the Second Hospital of Tangshan, Hebei Tangshan 063000, China. The College of Public Health of Xinjiang Medical University, Urumqi, China Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium. Department of Clinical and Experimental Medicine; Centre for Individualised Medicine; Linköping University; Linköping Sweden Department of Pathology , Beijing Thorax Tumor and Tuberculosis Hospital(Institute) , Beijing 101149 , P. R. China. Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan, Republic of China. Laboratory of Oral Infectious Diseases, Temple University Kornberg School of Dentistry, Philadelphia, PA 19140, USA; Department of Endodontology, Temple University Kornberg School of Dentistry, Philadelphia, PA 19140, USA LAL, Univ. Paris-Sud, CNRS/IN2P3, Université Paris-Saclay, Orsay, France Department of Environmental Engineering, Wuhan University, P.O. Box C319 Luoyu Road 129#, Wuhan 430079, China College of Food Science Qilu University of Technology Shandong China Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China. Cellular and Molecular Biology Lab , Beijing Thoracic Tumor Research Institute , Beijing 101149 , P. R. China. College of Biological Science and Technology Beijing Forestry University Beijing China BGI clinical laboratory-Shenzhen; Shenzhen 518083 China; BGI-Shenzhen; Shenzhen 518083 China North China Coal Medical College, Tangshan 063000. MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine Department of Anaesthesiology, School of Stomatology, The Fourth Military Medical University, Xi'an, China Beijing Red Cross Chaoyang Hospital, Beijing Respiratory Disease Research Center. Department of Pathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, Florida 33612, USA. National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing Clinical School of Second Military Medical University, Nanjing University School of Medicine, Nanjing, China Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland 21205. Department of Orthopaedics, First Affiliated Hospital of Soochow University, Suzhou, China Research Center of Interventional Neurooradiology, Beijing Hospital, Beijing 100730. Department of Oral Maxillo-facial Surgery,School of Stomatology,Shanghai Second Medical University. Shanghai 200011,China. College of Veterinary Medicine; South China Agricultural University; Guangzhou China Key Laboratory of Plateau Lake Ecology and Environment Change Institute of Plateau Lake Ecology and Pollution Management School of Resource Environment and Earth Science Yunnan University Chenggong, Kunming, Yunnan 650504 China Occupational Hygiene Division, Institute for Health Monitoring Inspection and Protection, Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079, China. BGI‐Diagnostics Shenzhen China; BGI Clinical Laboratories‐Wuhan Wuhan China Department of Gerontology Institute, General Hospital of PLA, Beijing. Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China. State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling 712100, China Statens Serum Institut, Department of Epidemiology Research, Copenhagen, Denmark Unilever Research Laboratorium Vlaardingen, 3133 AT Vlaardingen,1 Burnham Institute, La Jolla, California 92037, USA. Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China Key Laboratory of Shenzhen for Histocompatibility and Immunogenetics Shenzhen Blood Center Shenzhen P. R. China Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, China; Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, Hefei, China; Key Laboratory of Major Autoimmune Diseases, Anhui Province, Hefei, China Department of Ophthalmology, Eye Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100040, China Département des Sciences Biologiques, Université du Québec à Montréal, Montréal, Québec,1 and Department of Anesthesiology, Weihai Municipal Hospital, Weihai, Shandong, China Trauma Research Center, Fourth Medical Center of the Chinese PLA General Hospital, Beijing 100048, China. Department of Otolaryngology‐Skull Base Surgery Xiangya Hospital Central South University Changsha Hunan China Department of Plastic Surgery, Zibo Central Hospital, Zibo 255036. Paediatric Liver Disease Therapy and Research Center, 302 Hospital, Beijing, China Department of Anesthesiology, Xiangya Hospital, Hunan Medical University, Changsha 410008. Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education P.R.C., Inner Mongolia Agricultural University, Inner Mongolia, Hohhot 010018, China P.R. Department of Radiology, First Affiliated Hospital of Anhui Medical University, Hefei, PR China Department of Earth and Atmospheric Sciences, University of Houston, Houston, Texas, USA Institute for Environmental Health Inspection and Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021. Department of Cardiology, Guizhou Provincial People’s Hospital, Guiyang, China Department of Biological Chemistry, Johns Hopkins University, Baltimore, MD 21205. Department of Physics, University of Toronto, Toronto, Ontario M5S 1A7, Canada. Research Center for Cardiovascular Regenerative Medicine, Fu Wai Hospital, Beijing - China; Department of Cardiovascular Surgery, Fu Wai Hospital, Beijing - China State Key Laboratory of Tree Genetics and Breeding (Northeast Forestry University) School of Forestry, Northeast Forestry University Harbin China; School of Forestry Northeast Forestry University Harbin China Molecular Endocrinology Laboratory (H.Z., X.C., M.R.S.), Institut de Recherches Cliniques de Montréal, Montréal, Quebec, H2W 1R7 Canada. Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB), UMR 6303 CNRS-Université 3 , Bourgogne-Franche Comté, 9 Ave. A. Savary, BP 47 870, F-21078 Dijon Cedex, France Department of Health Toxicology, College of Public Health, Xinjiang Medical University, Urumqi, China Institute of Materia Medica Planting, Sichuan Academy of Traditional Chinese Medicine and Materia Medica, Nanchuan 648408. Animal Husbandry and Veterinary Institute, Hubei Academy of Agricultural Science, Wuhan, China. Key Laboratory of Prevention and Control Agents for Animal Bacteriosis (Ministry of Agriculture) Wuhan, China. College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China Shenzhen University. From the Departments of Neurology, (S.M.H., S.G., A.Z., N.H., H.Z., H.Y., H.D.R.) and Biostatistics (D.S.), MassGeneral Institute for Neurodegenerative Disease, MGH-NMR Center and Athinoula A. Martinos Center for Biomedical Imaging (A.Z., B.J., N.H., H.D.R.), Massachusetts General Hospital and Harvard Medical School, Charlestown, MA; Center for Parkinson's Disease and Other Movement Disorders (K.M., C.M.), Department of Neurology, Sergievsky Center and Taub Institute for Research on Alzheimer's... Department of Medical Physics, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China; Key Laboratory of Heavy Ion Radiation Biology and Medicine, Chinese Academy of Sciences, Lanzhou, China; Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province, Lanzhou, China Qinghai Provincial People's Hospital, Xining 010007. Harris Birthright Research Centre for Fetal Medicine Fetal Medicine Research Institute King's College Hospital London UK Soochow University School of Medicine, China Nanjing Municipal Center for Disease Control and Prevention; Jiangsu China WestChina-Frontier PharmaTech Company Limited, Chengdu 610041, China. Department of Anaesthesiology and Critical Care Medicine Peking University First Hospital Beijing China Department of Reproductive, Guangxi Medical University, Nanning, Guangxi, China. Shanghai Children's Hospital, Shanghai, China Occupational Disease Department, Qingdao Central Hospital, Qingdao 266042, China; Respiratory Department, Qingdao Central Hospital, Qingdao 266042, China. c Australian Synchrotron , Clayton , 3168 , Australia; d School of Chemistry, University of Melbourne , Melbourne , 3010 , Australia Department of Nephrology, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China Department of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. Medical Genetics Laboratory, Hunan Medical University, Changsha. Department of Colorectal Cancer Surgery, Shengjing Hospital of China Medical University, Shenyang 110000, China. Department of Cardiovascular and Thoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China. Department of Psychology, School of Public Health, Southern Medical University, Guangzhou 510515, China. Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing 100041. State Key Laboratory of Animal Nutrition; Institute of Animal Sciences; Chinese Academy of Agricultural Sciences; Beijing; PR China Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China. Dep. of Plant and Soil Sciences; Oklahoma State Univ.; Stillwater OK Department of Human Anatomy, Bengbu Medical College, Bengbu 233030, China. Anhui Provincial Key Laboratory of Digital Medicine and Smart Health, Bengbu Medical College, Bengbu 233030, China. Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006,China. Shenzhen Institute of Transfusion Medicine Shenzhen Blood Center Shenzhen China Department of Ultrasound Medicine Shengjing Hospital affiliated to China Medical University Shenyang China Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China. Key Laboratory of Breast Cancer Prevention and Therapy Ministry of Education Tianjin Medical University Cancer Institute and Hospital Tianjin Medical University Tianjin China Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston 77555-1019, USA. Department of Integrated Treatment Area 1 Affiliated Jinan Third Hospital of Jining Medical University Jining Medical University Jinan Shandong Province China Department of Pathology and Laboratory Medicine, College of Medicine, University of South Florida, Tampa 33612, USA. Department of Environmental Health, Shanxi Medical University, Taiyuan, China Department of Endocrinology, Key Laboratory of Endocrinology, Ministy of Health; Peking Union Medical College Hospital, Peking Union Medical College; Chinese Academy of Medical Sciences; Beijing School of Pharmacy, Chengdu. Central Laboratory, Peking University School and Hospital of Stomatology, Beijing, China School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, Anhui Province Department of Physiology, University of Leeds, Leeds LS2 9JT, United Kingdom Department of Respiratory and Critical Care Medicine, Rizhao Hospital of Traditional Chinese Medicine, Shandong Province 276800, China. Center for Medical Genetics, Hunan Key Laboratory of Medical Genetics & Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University From the , Changsha, Hunan 410078, China Chinese Academy of Sciences 1 Institute of Plasma Physics, , Hefei 230031, People’s Republic of China Department of Chemistry and Biochemistry; University of Delaware; Brown Lab; Newark; USA Department of Emergency Qingdao Municipal Hospital Qingdao Shandong China Department of Medicine, Albert Einstein College of Medicine, New York,New York 10461. Department of Respiratory disease Beijing Luhe Hospital Affiliated to Capital Medical University Beijing China Department of Urology, First Teaching Hospital, Norman Bethune University of Medical Sciences, Changchun. University of Manchester, United Kingdom Laboratory of Medicinal Chemistry, National Cancer Institute, NIH, Bethesda, Maryland 20892. Institute of Human Virology, Sun Yat-Sen University, Guangzhou; Department of Cell Biology, Southern Medical University, Guangzhou, China Department of Clinical Immunology Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Division of Gastroenterology University of Southern California Los Angeles CA USA Department of Stomatology, 210 Hospital of Chinese PLA, Dalian. Department of Orthopedics West China HospitalSichuan University Chengdu China Department of Arteriosclerosis, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China. 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Key Laboratory of Hormones and Development (Ministry of Health) Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China Clinical Laboratory of BGI Health Shenzhen China Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China State Key Laboratory of Food Science and Technology; School of Food Science and Technology; Jiangnan University; Wuxi Jiangsu China; Synergetic Innovation Center of Food Safety and Nutrition; Wuxi Jiangsu China Department of Radiology; Daqing Longnan Hospital of the 5th Affiliated Hospital of Qiqihaer Medical College; Daqing China State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China P.R.; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122 Jiangsu, China P.R.; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu, China P.R.; Wuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch, Wuxi, China P.R. Department of Thoracic Surgery the First Hospital of Jilin University Changchun, Jilin China; Key Laboratory of Zoonosis Research Ministry of Education College of Veterinary Medicine Jilin University Changchun, Jilin China Arkansas Biosciences Institute Department of Biological Science Arkansas State University Jonesboro AR USA; Department of Bioscience and Bioengineering Dalian University of Technology Dalian China The China Conservation and Research Center for Giant Panda; Sichuan China Department of Pathology, Peking University First Hospital, Beijing 100034, China. Nebraska Center for Virology and School of Biological Science, University of Nebraska, Lincoln, Nebraska 68588 State Key Laboratory of Pollution Control and Resources Reuse, Tongji University, Shanghai, 200092, PR China Department of Thyroid Surgery, the First Hospital, China Medical University, Shenyang 110001, China. Department of Physics, Nanjing University, Nanjing, China Jiangnan University State Key Laboratory of Food Science and Technology, School of Food Science and Technology Wuxi China zhanghuigwzx@gmail.com. Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 Department of Ophthalmology, University of Michigan, Ann Arbor 48109. Laboratory of Seed Science and Technology State Key Laboratory of Crop Genetics and Germplasm Enhancement Jiangsu Collaborative Innovation Center for Modern Crop Production Nanjing Agricultural University Nanjing Jiangsu China Department of Pathology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200090, China. Institute of Nephrology, Beijing Medical University. Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou 510515, China. Guangdong Provincial Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou 510515, China. Department of Clinical and Experimental Medicine; Linkoping University; Linkoping Sweden; CIMed, Centre for Individualised Medicine; Faculty of Health Sciences; Linkoping University; Linkoping Sweden Department of Application of Heavy Ions, Institute of Modern Physics, The Chinese Academy of Sciences, Lanzhou. Department of Biochemistry, Charing Cross and Westminster Medical School, University of London, United Kingdom. Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, D-76131 Karlsruhe, Germany, Institute of Organic Chemistry, University of Regensburg, D-93040 Regensburg, Germany; Laboratory of Inorganic Chemistry, University of Helsinki, P.O. Box 55 (A.I. Virtasen aukio 1), FIN-00014 University of Helsinki, Finland; Laboratory of Organic Chemistry, University of Jyväskylä, P.O. Box 35, FIN-40014 University of Jyväskylä, Finland; Institute of Nanotechnology (INT), Karlsruhe... State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Chengdu, China; Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China State Key Laboratory of Animal Genetic Engineering Vaccine YEBIO Bioengineering Co., Ltd. of Qingdao Qingdao China Department of Cell Biology, Vanderbilt Cancer Center, Vanderbilt University, Nashville, TN, USA. Department of Cardiology, Friedrich-Alexander-University Erlangen-Nürnberg, Germany. zhh86@hotmail.com Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. The Innovation Centre of Food Nutrition and Human Health; College of Food Science and Nutritional Engineering; China Agricultural University; Beijing China; Key Laboratory of Functional Dairy; College of Food Science and Nutritional Engineering; China Agricultural University; Beijing China; Beijing Laboratory of Food Quality and Safety; College of Food Science and Nutritional Engineering; China Agricultural University; Beijing China Department of Pathology, Anzhen Hospital, Beijing. Laboratory of Environmental Mutagensis, Department of Biological Scicences, Western Illinois University, Macomb, IL 61455, USA. State Key Laboratory of Food Science & Technology; School of Food Science and Technology; Jiangnan University; Wuxi China Research Center for Biological Therapy, Beijing 302 Hospital, Beijing Institute of Infectious Diseases Beijing Laboratory for Cardiovascular Precision Medicine Beijing China; Department of Cardiac Surgery, Beijing ChaoYang Hospital Capital Medical University Beijing China Department of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University, Nanning, China Crop and Soil Sciences; University of Georgia Griffin Campus; Griffin GA USA Rizhao City Hospital of Traditional Chinese Medicine, Rizhao 276800, China. PUMC Hospital, CAMS, Beijing. Department of Hematology, The Affiliated Hospital of Jining Medical University, Jining 272000, China. Shanghai Key Laboratory of Tissue Engineering Shanghai P.R. China Laboratory of Medicinal Chemistry, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892. Qingdao Central Hospital Affiliated to Qingdao University, Qingdao 266042, China. Affiliated Yancheng Hospital, Medical College of Southeast University, Yancheng, China Interventional Neuroradiology Research Center & Neurosurgery Department, Beijing Hospital, Beijing, PR. China Department of Toxicology, Chinese Academy of Preventive Medicine, Beijing. Department of Gastroenterolgy; Third Hospital of Peking University; Beijing China Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University; Anhui Provincial Laboratory Population Health and Eugenics, Hefei 230032, China. Department of Respiratory and Critical Care Medicine, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; the First Affiliated Hospital, Southern University of Science and Technology), Shenzhen Institute of Respiratory Diseases in Shenzhen People's Hospital, Shenzhen 518020,China. Department of Chemistry, Jilin University, Changchun 130023, People's Republic of China. Institute of Stomatology College of Stomatology Nanjing Medical University Nanjing China Colin Ratledge Center for Microbial Lipids; School of Agricultural Engineering and Food Science; Shandong University of Technology; Zibo Shandong China Research Center of Clinical Epidemiology Peking University Third Hospital Beijing China Department of Radiology, The First Hospital of Lanzhou University, Lanzhou 730000, China. Division of Psychiatry, University College London, London, UK;; National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health, Peking University Institute of Mental Health (Sixth Hospital), Beijing, China;; Dementia Care and Research Center, Peking University Institute of Mental Health (Sixth Hospital), Beijing, China; Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, Maryland 20850, Department of Chemistry, University of New Mexico, Albuquerque, New Mexico 87131, Illinois Institute of Technology, Chicago, Illinois 60616, Advanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439, and Department of Structural Chemistry, University of Göttingen, Tammannstrase 4, 37077 Göttingen, Germany Department of Obstetrics Gansu Provincial Hospital Lanzhou Gansu China Renal Division, Peking University First Hospital, People’s Republic of China; Peking University Institute of Nephrology, People’s Republic of China; Key Laboratory of Renal Disease, Ministry of Health of China, People’s Republic of China; Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, Beijing, People’s Republic of China Louise Coote Lupus Unit, Guy’s and St Thomas’ Hospital NHS Foundation Trust, London, UK Division of Toxicology, Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis 46202, USA. Flower Research Institute, Yunnan Academy of Agriculture Science, Kunming 650205, Yunnan, China Department of Vaccine Engineering, Beijing Institute of Basic Medical Sciences, Beijing, China. Imperial College School of Medicine (Infectious Diseases & Medical Microbiology; Central Biomedical Services; Department of Histopathology; and Molecular Pathology), Charing Cross Campus, London, UK Department of Emergency, the Second Affiliated Hospital Harbin Medical University Harbin P. R. China Department of Dermatology Baoan Central Hospital Shenzhen China Lancaster Environment Centre, University of Lancaster, Bailrigg, Lancaster, LA1 4YQ, United Kingdom Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing. National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, China AIDS Reference Lab Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu 610081, China. Laboratory for Experimental Brain Research, University of Lund, Sweden. Key Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing, Haidian, China Department of Medical Oncology, Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, 02115, Boston, Massachusetts, USA Department of Biochemical Engineering, University College London, London WC1E 6BT, U.K. Department of Oncology, Institute of Integrative Oncology, Tianjin Union Medical Center of Nankai University, Tianjin 300121, China. College of Horticulture, Northeast Agricultural University, Xiangfang District, Harbin 150030, China. First Department of Spinal Surgery, Changzheng Hospital Affiliated to Second Military Medical University, Shanghai 200003, China. Department of Obstetrics and Gynaecology The First Affiliated Hospital of Chongqing Medical University Chongqing China School of Medical Technology, Qiqihar Medical University, Qiqihar 161006, China. Changsha University of Science and Technology 1 School of Physics and Electronic Science, , Changsha 410076, People’s Republic of China Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, PR China; Department of Biology, Lanzhou University, Lanzhou, Gansu 730000, PR China; Physical and Chemical Center, Henter, Hebei University, Baoding 071002, PR China. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhengzhou University , Zhengzhou 450052, China Department of Gastrointestinal Colorectal and Anal Surgery China‐Japan Union Hospital of Jilin University Changchun Jilin China Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China. Biological Physics Group, School of Physics & Astronomy The University of Manchester Manchester UK National Key Laboratory of Biomacromolecules; Institute of Biophysics; Chinese Academy of Sciences; Beijing 100101, China Department of Nuclear Medicine, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, China. Department of Pediatric Pneumology, Shengjing Hospital of China Medical University, Shenyang 110004, China Institute for Computational Sciences and Engineering, Qingdao University, Shandong 266071, People’s Republic of China, and Centre for Computational Molecular Science, Chemistry Building, The University of Queensland, Qld 4072, Brisbane, Australia Department of pathology, Peking University First Hospital, Beijing 100034, China. Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China Department of Life Scinec & Biomedical Engineering, Zhejiang University, Hangzhou 310027. Department of Gynecology, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China. Institut d’Electronique Fondamentale, UMR CNRS 8622, University Paris Sud 11, 91405 Orsay, France Department of Endocrinology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Obstetrics Eastern District of the Fourth Hospital of Hebei Medical University Hebei China Shanghai Institute of Materia Medica, Academia Sinica, Shanghai. Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry, Dallas, TX, USA Graduate School, Southern Medical University, Guangzhou, Peoples’ Republic of China; The Department of Joint Surgery, The Second Hospital of Tangshan, Tangshan, Peoples’ Republic of China University Women's Hospital Basel, Schanzenstrasse 46, CH-4031 Basel, Switzerland. hzhang@uhbs.ch Department of Medical Molecular Biology, Tongji Medical University, Wuhan 430030. Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027. School of Life Science and Engineering, Foshan University, Foshan, China Dorrance H. Hamilton Laboratories, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. Xuzhou First People's Hospital Xuzhou China New Material Research Institute, Chemistry and Chemical Engineering College, Hunan University, Changsha, 410082, People's Republic of China. Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing. School of Marxism Studies, Bengbu Medical College, Bengbu, 233030, China. School of Ecology and Environmental Science, Yunnan University, China. Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China. Department of Pathology and Laboratory Medicine, University of Rochester Medical Centre, 601 Elmwood Ave, Rochester, NY 14642, USA Department of Pathology and Physiology, Shanxi Medical University, China. Department of Respiratory Disease, Peking Union Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China. State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi International Joint Research Center for Oral Diseases, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, the Fourth Military Medical University, Xi’an, China Department of Biochemistry, Charing Cross and Westminster Medical School, London, UK. Department of Otorhinolaryngology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025. Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie (IMPMC), Sorbonne Université, CNRS UMR 7590, MNHN, 4, place Jussieu, Paris 75005, France; Shandong Key Laboratory of Optical Communication Science and Technology, School of Physics Science and Information Technology, Liaocheng University, Liaocheng 252059, China Department of Rheumatology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China Xijing Hospital of Digestive Diseases; Xijing Hospital, Fourth Military Medical University; Xi'an; Shaanxi Province; China Center for the Built Environment; University of California, Berkeley; Berkeley CA USA Department of Dermatology Peking Union Medical College Hospital Beijing China; Eight‐year MD Program Peking Union Medical College Beijing China Dorrance H. Hamilton Laboratories, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA. State Key Laboratory of Agricultural Microbiology, Hubei Key Laboratory of Insect Resource Application and Sustainable Pest Control, and Institute of Urban and Horticultural Entomology, College of Plant Science and Technology Huazhong Agricultural University Wuhan Hubei China College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China. Department of Biology, James Madison University, Harrisonburg, Virginia 22807. Yangzhou Medical College. West China University of Medical Sciences, Chengdu. Department of Ophthalmology, The Affiliated Hospital of Guizhou Medical University, Guiyang 550031, China. Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain. Key Laboratory of Dairy Biotechnology and Bioengineering, Education Ministry of P. R. China, Department of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China P.R.; Synergetic Innovation Center of Food Safety and Nutrition, Northeast Agricultural University, Harbin 150030, China P.R. Shenzhen Blood Center Immunogenetics Laboratory Shenzhen Guangdong 518035 China The Reproductive Medicine Center, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China Jiangsu Institute of Clinical Immunology, Suzhou 215000, China Jiangsu Key Laboratory of Clinical Immunology, Soochow University, Suzhou 215000, China. Department of Anaesthesiology, School of Stomatology, Fourth Military Medical University, Xi'an, Shaanxi Province, China Center of Analysis and Test, Chengdu University of Science and Technology, 610065 Chengdu. Department of the First Internal Medicine, Hebei Provincial, Hospital, Shijiazhang. Danyang People's Hospital of Jiangsu Province, Jiangsu, China General Surgery Center, Second Department of Hepatobiliary Surgery, Guangdong Provincial Research Center for Artificial Organ and Tissue Engineering, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China. College of Agronomy and Biotechnology Southwest University Chongqing China; Engineering Research Center of South Upland Agriculture Ministry of Education Southwest University Chongqing China Department of Otorhinolaryngology Head and Neck Surgery, Tianjin HuanHu hospital, Tianjin 300350, China. Xinjiang Vocation & Technology College of Communications, Urumuqi, China Fourth Hospital in Wuhan, Wuhan 430030. Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Md. Department of Hand Surgery, Beijing Ji Shui Tan Hospital, Beijing, China Lancaster Environment Centre, Lancaster University, Lancaster, LA1 4YQ, United Kingdom Pediatric Endocrinology Unit, and College of Plant Protection and Shaanxi Key Laboratory of Molecular Biology for Agriculture, Northwest A&F University, Yangling, 712100, P. R. China State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Radiotherapy, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. Geisinger Health System, Department of Orthopaedics, Danville, PA 17822, USA Department of Urology; Shandong Provincial Hospital affiliated to Shandong University; Jinan Shandong China Key Laboratory of Dairy Biotechnology and Bioengineering, Education Ministry of P.R. China, Department of Food Science and Engineering, Inner Mongolia Agricultural University, 306 Zhaowuda road, Hohhot 010018, China State Key Laboratory of Food Science and Technology Jiangnan University Wuxi Jiangsu China; School of Food Science and Technology Jiangnan University Wuxi Jiangsu China; National Engineering Research Center for Functional Food Jiangnan University Wuxi Jiangsu China; Wuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch Wuxi Jiangsu China State Key Laboratory of Animal Nutrition Institute of Animal Science Chinese Academy of Agricultural Science Beijing China Tianjin Second People Hospital Tianjin Hepatology Institute, Tianjin 300192, China. Department of Anaesthesiology, Stomatology Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China Network of Excellence for Functional Biomaterials (NFB); National University of Ireland; Galway, Ireland Department of Abdominal Surgery, Cancer Hospital, National Laboratory of Molecular Oncology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100021. Department of Atherosclerosis, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China. School of Agriculture Ningxia University Yinchuan China Department of Earth Sciences; University of Cambridge; Cambridge; UK State Key Laboratory of Food Science and Technology; School of Food Science and Technology; Jiangnan University; Wuxi China Department of Neurology National Center of Gerontology Beijing Hospital Beijing China Department of Microbiology and Immunology, University of Texas Medical Branch at Galveston 77555. Department of Pathology and Laboratory Medicine, University of Texas—Houston Medical School,1 and Institute of Hematology, Hexi Hospital, Tianjin. Department of Head and Neck/Thoracic Medical Oncology, the First People's Hospital of Foshan, Foshan, China. fengwn81@126.com. School of Chemistry and Biological Engineering University of Science and Technology Beijing Beijing China Jiangsu Engineering Technology Research Center of Mutton Sheep and Goat Industry, Nanjing Agricultural University, Nanjing 210095, P.R. China Department of Medical Biochemistry, College of Medicine, Ohio State University, Columbus 43210-1218. a State Key Laboratory of Natural & Biomimetic Drugs, School of Pharmaceutical Sciences, and Medical and Healthy Analysis Center , Peking University , Beijing, 100083, China Rheumatology Department, Chinese PLA General Hospital, Beijing. Administration Office,Chongqing Health Center for Women and Children,Chongqing 401120,China. The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049 P.R.China Department of Cardiology, People's Hospital, Beijing Medical University, Beijing 100044, China. University of Kassel Department of Natural Science, , D-34132 Kassel, Germany Department of Surgery, University of Alberta, Edmonton, Canada. Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA. Department of Joint Surgery, the Second Hospital of Tangshan, Tangshan 063000, Hebei, China. Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205. Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education P.R. China, Inner Mongolia Agricultural University, Inner Mongolia, Hohhot 010018, China P.R. Department of Medical Records, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical Collge, Beijing 100021, China. Department of Exercise Physiology, Beijing Sport University, Beijing, China Department of Stomatology, PLA General Hospital, Beijing 100853. Department of Clinical Medicine; Zhongshan School of Medicine; Sun Yat-sen University; Guangzhou China Department of Dermatology and Allergy, Herlev and Gentofte Hospital University of Copenhagen Hellerup Denmark School of Biomedical Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom; Chinese Academy of Sciences 1 Key Laboratory of Transparent Opto-Functional Inorganic Materials, Shanghai Institute of Ceramics, , 200050 Shanghai, China; Max-Planck-Institut für Chemische Physik fester Stoffe 2 , Nöthnitzer Str. 40, 01187 Dresden, Germany Department of General Surgery, Peking University First Hospital, Beijing 100034, China. Chinese Mechanical Engineering Society, Beijing, China Department of Anesthesiology, Xiangya Hospital, Hunan Medical University, Changsha. Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724. Department of Hematology, The Second Affiliated Hospital of Soochow University, Suzhou 215000. Department of Pathogenic Biology and Immunology Medical School Southeast University Nanjing China Department of Neurology, Renmin Hospital of Wuhan University, Wuhan 430060, China. Department of Otorhinolaryngology, Head and Neck Surgery, Qilu Hospital, Shandong University, Jinan, China Key Lab of Agriculture Animal Genetics, Breeding, and Reproduction of Ministry of Education; College of Animal Science and Technology; Huazhong Agricultural University; Wuhan 430070 People's Republic of China Department of Oral and Maxillofacial Surgery, School of Stomotology, Shanghai Second Medical University. Shanghai 200011,China. Department of Microbiology, College of Biological Sciences, China Agricultural University, Beijing 100094, China. Department of Consultation Liaison, Peking University Sixth Hospital, Beijing 100191, China. Orthopedic Surgery Department, Zhujiang Hospital of First Military Medical University, Guangzhou, Guangdong, P. R. China 510282. From the Departments of Neurology (Drs. E.M. Frohman, Zhang, Dewey, Hawker, Racke, and T.C. Frohman) and Ophthalmology (Dr. E.M. Frohman) and the Center for Immunology (Dr. Racke), University of Texas Southwestern Medical Center, Dallas. State Key Joint Lab. of Environ. Simulation and Pollution Control, Dept. of Environ. Sci. and Eng., Tsinghua Univ., Beijing 100084, China. hong-xun@263.net Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China. Renal Division of Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, People's Republic of China State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China P.R.; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, Wuxi 214122, China P.R. State Key Laboratory of Food Science and Technology Jiangnan University Wuxi Jiangsu P.R. China; School of Food Science and Technology Jiangnan University Wuxi Jiangsu P.R. China; National Engineering Research Center for Functional Food Jiangnan University Wuxi Jiangsu P.R. China; Wuxi Translational Medicine Research Center Jiangsu Translational Medicine Research Institute Wuxi Branch Wuxi Jiangsu P.R. China National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, CAMS, PUMC, Beijing 100005, China. Department of Ultrasonography, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, School of Clinical Medicine, University of Electronic Science and Technology of China, Chengdu, China. 809196529@qq.com. Biological Engineering Center; Guangzhou Institute of Advanced Technology; Chinese Academy of Sciences; Guangzhou China State Key Laboratory of Fine Chemicals (Dyes and Surfactants), Dalian University of Technology, 116012 Dalian. Institute of Medical Biochemistry, Guangdong Medical College, Zhanjiang, 524023. Department of Chemistry, University of Illinois at Chicago, Chicago, IL 60680, USA. State Key Laboratory of Dye and Surfactant Fine Chemicals, Dalian University of Technology, Dalian, 116012. Division of Infectious Diseases, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China Department of Oral Biology, Clinic of Oral Rare and Genetic Diseases, School of Stomatology, Air Force Military Medical University (the Fourth Military Medical University), Xi’an, China Laboratory of Molecular Diagnostics, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, China Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing. Allergy and Cancer Center Otorhinolarygology Hospital The First Affiliated Hospital of Sun Yat‐sen University Guangzhou China Agassiz Research and Development Centre PO Box 1000 6947 Highway 7 Agassiz BC Canada Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Institute of High Energy Physics, Beijing, China Institute of Medicinal Biotechnology, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050. Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization Ministry of Agriculture South China Sea Fisheries Research Institute Chinese Academy of Fishery Sciences Guangzhou China; Shanghai Ocean University Shanghai China Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA. Department of Orthopedics, the Second Affiliated Hospital of Soochow University, Osteoporosis Institute of Soochow University, Suzhou 215004, China. State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, People’s Republic of China, and Department of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, Tennessee 37996 BGI‐Diagnostics Shenzhen China; BGI Clinical Laboratories‐Shenzen Shenzhen China ISIC, and Lausanne Centre for Ultrafast Science (LACUS) 1 Laboratory of Ultrafast Spectroscopy, , Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland Tongji University School of Medicine, 301 Yanchang Road, Shanghai 200072, China. Institute of pharmacology and Toxicology, Academy of Military Sciences, Beijing, 100850. Department of Epidemiology, School of Public Health, Harbin Medical University, Harbin 150081, China. Department of Helminthiasis, Center for Disease Prevention and Control of Henan Province, Zhenzhou, China Zhuhai Campus, Zunyi Medical University, Zhuhai 519041, China. Department of Geratology, Shanghai East Hospital, Tongji University, Shanghai, China Department of Biological Sciences, Texas Tech University, Lubbock, Texas 79409 (H.Z.) Department of Endocrinology and Metabolic Diseases Leiden University Medical Center Leiden The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine Leiden University Medical Center Leiden The Netherlands Key Laboratory of Dairy Biotechnology and Bioengineering, Education Ministry of China, Department of Food Science and Engineering, Inner Mongolia Agricultural University, 306 Zhaowuda road, 010018 Hohhot, China P.R. State Key Laboratory for Conservation and Utilization of Subtropical Agro‐Bioresources Guangxi University Nanning China; School of Animal Science and Technology Guangxi University Nanning China Department of Pharmaceutics College of Pharmacy, University of Wisconsin, Madison, WI 53706, USA Department of Life Science & Biomedical Engineering, Zhejiang University, Hangzhou 310027. AnHui College of Traditional Chinese Medicine, Wuhu 241000, China. Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials, Ministry of Education, Shandong University, Jinan 250061, China Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research U.S. Food and Drug Administration Silver Spring Maryland USA Henan Sesame Research Center Henan Academy of Agricultural Sciences Zhengzhou China Center for Advanced Biotechnology and Medicine and Graduate Program in Molecular Genetics and Microbiology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA. Institute of Medicinal Plant Cultivation, Sichuan Academy of Traditional Chinese Medicinal and Pharmacy, Nanchuan. Department of Pathology and Lab Medicine; Perelman School of Medicine, University of Pennsylvania; Philadelphia Pennsylvania USA Department of Dermatology and Venereal Disease; Xuanwu Hospital; Capital Medical University; Beijing China The First Affiliated Hospital of Nanjing Medical University Nanjing, Jiangsu, China Department of Endocrine and Metabolic Diseases, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou City, Zhejiang Province, P. R. China Physical and Chemical Inspection Institute, Jiangsu Provincial Center for Disease Control and Prevention, Jiangsu, 210028, China. Peking University People's Hospital, Peking University Hepatology Institute, Beijing, China; Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Beijing, China; Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Emerging Infectious Diseases, Beijing, China Department of Pharmacology, Columbia University, New York, New York, USA. Department of Oral and Maxillofacial Surgury, School of Stomatology, Shanghai Second Medical University, Shanghai 200011, China. Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, State Key Laboratory of Structural Chemistry and Laboratory of Materials Chemistry and Physics, Fuzhou, Fujian 350002, People’s Republic of China Department of Neurology, Chinese PLA General Hospital, Beijing 100853, China. Unilever Research and Development Vlaardingen, Vlaardingen, The Netherlands School of Life Sciences, Lanzhou University, Lanzhou, China Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Belgium. Key Laboratory of Chicken Genetics and Breeding Ministry of Agriculture Key Laboratory of Animal Genetics, Breeding and Reproduction Education Department of Heilongjiang Province College of Animal Science and Technology Northeast Agricultural University Harbin China Environmental Engineering Research Centre, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 Department of Cardio-Thoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, National Children's Medical Center, Shanghai 200127, China Shanghai Institution of Pediatric Congenital Heart Disease, Shanghai 200127, China. Biological Science Research Center Southwest University Chongqing China; Chongqing Key Laboratory of Sericulture Science Chongqing China Department of Gynecological Oncology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin 300199, China. Department of Ophthalmology, Third Hospital, Beijing Medical University. Environmental Science Department Lancaster University Bailrigg Lancaster LA1 4YQ Institute of Integrated Medicine of TCM-WM, Hunan Medical University, Changsha. Shenzhen Emergency Center, Shenzhen 518035, China. The University of Manchester School of Physics and Astronomy, , Manchester, M60 1QD, United Kingdom Dalian Medical University, China Animal Husbandry Bureau of Yongji County, Tianjin Street, Jilin,132100, Jilin Province, PR China. Department of Neurosurgery, Xuzhou Central Hospital, Xuzhou 221000, China. Internal Medicine Department, Songming County People’s Hospital, Kunming, China Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Head and Neck Molecular Diagnostic Pathology, Beijing 100730, China. Department of Dermatology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China; Institute of Dermatology Shanghai Jiao Tong University School of Medicine Shanghai China College of Animal Science and Technology/Co-Innovation Center for Zoonotic Infectious Diseases in the western region; Shihezi University; Shihezi China Department of Dermatovenereology West China Hospital Sichuan University Chengdu 610041, Sichuan Province China From Neurology Clinical Trials Unit (Drs. Traynor and Cudkowicz, K.L., Ferrante, M. O'Brien, Y. Yu, M. Fantasia, K. Newhall), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Neurology (Dr. Shefner and J. Taft), SUNY Upstate Medical University, Syracuse, NY; Department of Biostatistics (Dr. Betensky and H. Zhang), Massachusetts General Hospital Biostatistics Center, Harvard Medical School, Boston; Department of Neurology and Neuroscience (Dr. Beal), Weill Medical College... Life Sciences Division, Los Alamos National Laboratory, NM 87545. Key Laboratory of Saline‐Alkali Vegetation Ecology Restoration, Northeast Forestry University Ministry of Education Harbin China; College of Life Science Northeast Forestry University Harbin China First Hospital, Jilin University, Changchun, China National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China. Center for Human Virology, Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. Department of Child and Adolescent Health, Shandong Medical University, Ji'nan. Department of Gastrointestinal Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China. The Emergency and Intensive Care Center Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Laboratory of Rheumatology Research, Affiliated Anhui Provincial Hospital, Anhui Medical University, Hefei, China Beijing Tropical Medicine Research Institute. Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520-8034, USA. heping.zhang@yale.edu Key Laboratory of Polymer Material Advanced Manufacturings Technology of Shandong Provincial; College of Electromechanical Engineering; College of Sino-German Science and Technology; Qingdao University of Science and Technology; Qingdao 266061 Key Laboratory of Tropical Marine Bio‐resources and Ecology Chinese Academy of Sciences Beijing China Nanjing University 2 Institute of Theoretical and Computational Chemistry, School of Chemistry and Chemical Engineering, , Nanjing 210093, People’s Republic of China State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China P.R.; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China P.R.; (Yangzhou) Institute of Food Biotechnology, Jiangnan University, Yangzhou 225004, China P.R.; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, China P.R.; Wuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch, Wuxi 214122, China P.R. Center for Dental and Oral Medicine and Cranio-maxillofacial Surgery, Clinic for Masticatory Disorders and Complete Dentures, University Hospital Balgrist and Institute of Neuropsychology, University of Zürich, Plattenstrasse 11, CH-8028 Zürich, Switzerland; Department of Surgery, Northwestern University, Chicago, IL, USA; and Institute of Biomedical Engineering, ETH & University of Zürich, Switzerland; Central China Normal University, Wuhan, China;Department of Physics and Technology, University of Bergen, Bergen, Norway Structural Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Department of Cancer Prevention Center, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China. Department of Pathology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China. Department of Orthopaedics, Xiangya Hospital, Hunan Medical University, Changsha. Institute of Optoelectronic Material and Technology; South China Normal University; Guangzhou 510631; P. R. China Institut d'Electronique Fondamentale; UMR 8622 CNRS; University Paris Sud; 91405 Orsay cedex, France Department of General Surgery, Zhongshan Hospital, Shanghai Medical University. Department of Hematology, the Affiliated Hospital of Jining Medical University, Jining 272000, China. Department of Molecular Biology, Jilin University, Changchun, People's Republic of China. Department of Microbiology and Immunology, University of Arizona, Tucson 85724, USA. State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 35002, People’s Republic of China Department of Neurosurgery, the First Hospital of China Medical University, Shenyang 110001, China. Department of Endocrinology, First Affiliated Hospital, He-nan Medical University, Zhengzhou. Otolaryngology Institute of Fujian Province, Department of Otolaryngology, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005. Department of Chemistry, Jilin University, 130023 Changchun. Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Centre, Xi’an, China; Key Laboratory of Environment and Genes Related to Diseases (Xi’an Jiaotong University), Ministry of Education of China, Xi’an, China Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, China. Department of Thyroid Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China Department of Obstetrics and Gynecology The First Affiliated Hospital of Chongqing Medical University Chongqing People's Republic of China Department of Horticulture, Zhejiang University, Hangzhou, P.R. China From the Departments of Neurology (C.T.M., A.B., M.G.) and Radiology (C.B., S.S., M.C., P.Y., J.G.), University of Pennsylvania, Philadelphia; Department of Neurology (D.L.), Drexel University, Philadelphia, PA; and Department of Computer Science and Centre for Medical Imaging Computing (H.Z.), University College London, London UK. Los Alamos National Laboratory, Los Alamos, NM, USA. College of Animal Science and Technology Jiangxi Agricultural University Nanchang 330045 China Center of Dacryology, Second Affiliated Hospital of Ist Military Medical University, Guangzhou 510282, China. Clinical Laboratory, Shanghai Children's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200062, China. Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao, China. 17853290093@163.com. Will Rogers Pulmonary Research Laboratory, Cornell University MedicalCollege, White Plains, New York, USA. Department of Rheumatology and Immunology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital , 600 Yishan Road , Shanghai 200233, China . email: shengmingdai@163.com Department of Biological Sciences, Purdue University, West Lafayette, Indiana 49707-1392 Institute of New Energy Material Chemistry, Department of Materials Chemistry, N & T Joint Academy, Nankai University, Tianjin 300071, China, and Australian Key Centre of Microanalysis & Microscopy and School of Chemistry, The University of Sydney, New South Wales 2006, Australia Department of Otolaryngology Head and Neck Surgery,Renji Hospital, Medical College of Shanghai Jiaotong University. Departments of aNeurology and Neurological Sciences and Institute of Applied Ecology; Chinese Academy of Sciences; Shenyang China Department of Epidemiology, Harbin Medical University, Harbin 150001, China. College of Animal Science and Technology, Northeast Agricultural University, Harbin, Heilongjiang, China PET/CT Center, First Affiliated Hospital of Shenzhen University, Shenzhen 518052, China. Department of Imaging, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Institute of Medicinal Plant Cultivation, Sichuan Academy of Traditional Chinese Medicine and Pharmacy, Nanchuan. Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China. Department of Biochemistry and the Whitaker Cardiovascular Institute, Boston University School of Medicine, Massachusetts 02118, USA. Psychophysiology Laboratory, Institute of Physiological Sciences, Wannan Medical College, Wuhu 241002, China. Department of Otolaryngology, East Hospital, Shanghai 200120. Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou, China The Second Affiliated Hospital of Zhengzhou University Department of Obstetrics and Gynecology Zhengzhou China. Department of Biomedical Sciences and Center for Craniofacial Research and Diagnosis, Texas A&M University College of Dentistry, Dallas, TX, USA Department of Oncology The First Affiliated Hospital of Guangdong Pharmaceutical University Guangzhou China Department of Epidemiology and Biostatistics Arnold School of Public Health University of South Carolina Columbia SC USA Environmental Science Dep., LEC Lancaster Univ. Lancaster LA1 4YQ UK Department of Radio Electronics, Sichuan University, Chengdu 610064. Jiangnan University State Key Laboratory of Food Science and Technology, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology Wuxi China. The Graduate School of the Chinese Academy of Sciences Fujian Institute of Research on the Structure of Matter, State Key Laboratory of Structural Chemistry, , Fuzhou, Fujian 350002, People’s Republic of China Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100021, China. Immunogenetics Laboratory Shenzhen Blood Center Shenzhen Guangdong 518035 China State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, China Institute of Medical Biology Chinese Academy of Medical Sciences & Peking Union Medical College Yunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases Kunming China Max-Planck-Institut für Chemische Physik fester Stoffe, Nöthnitzer Straße 40, 01187 Dresden, Germany; Key Laboratory of Transparent Opto-Functional Inorganic Materials, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050, China Department of Respiratory and Critical Care Medicine, Ri Zhao Hospital of Traditional Chinese Medicine, Rizhao 276800, China. Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, ShanXi, Xi'an, China Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20007. College of Materials Science and Technology; Nanjing University of Aeronautics and Astronautics; Nanjing; P. R. China Department of Neurosurgery, the First Hospital of China Medical Uinversity, Shenyang 110001, China. Second Deople's Hospital, Xianyang 712000. Department of Dermatology, Institute of Biomedicine and Surgery, Linköping University, SE-581 85 Linköping, Sweden. hong.zhang@ibk.liu.se Peking Union Medical College Hospital Beijing China Jilin Medical University, Jilin 132013, Jilin, China. School of Public Health; Shandong University; Jinan 250012 China From the School of Biomedical Sciences, University of Leeds, Leeds, UK. Development Clinical Pharmacology Asia/PC; Bayer HealthCare Global R&D Center; Beijing China State Key Laboratory of Food Science and Technology; School of Food Science and Technology; Jiangnan University; Wuxi China; Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province; Jiangnan University; Wuxi China The Royal Marsden NHS Foundation Trust, UK Department of Epidemiology, the Fourth Military Medical University, Xi'an 710033, China. Department of Otolaryngology-Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China. Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission,Chongqing 400020,China Laboratory Medicine Center of the Second Hospital of Shandong University,Jinan 250033,China. State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China. Funding provided by National Natural Science Foundation (No. 31201477) Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China Department of Mathematical Sciences, Indian University, Purdue University Fort Wayne, Indiana 46805, USA. University Women's Hospital of Basel, Switzerland. Department of Cardiology, The Eight Affiliated Hospital, Sun Yat-sen University, Shenzhen, China Department of Surgery and Center for Pediatric Cardiac Surgery, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Science, Beijing, China Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences, and Key Laboratory of Integrated Pest Management of Tropical Crops, Ministry of Agriculture, Haikou, Hainan 571101, China Key Laboratory of Plant Nutrition and Agri‐environment in Northwest China Ministry of Agriculture College of Natural Resource and Environment Northwest A&F University Yangling Shaanxi China Heart Center, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Pediatric Congenital Heart Diseases, National Children's Medical Center, Shanghai 200127, China. Central Laboratory, School and Hospital of Stomatology, Peking University, Beijing, China NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Program in Physiological Genomics, Microbiome Consortium, Center for Hypertension and Personalized Medicine, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio Department of Pathology Fudan University Shanghai Cancer Center Shanghai China; Department of Oncology Shanghai Medical College Fudan University Shanghai China Animal Nutrition Institute Sichuan Agricultural University Ya'an Sichuan China Institut d’Electronique Fondamentale, UMR 8622 CNRS, Université Paris-Saclay, 91405 Orsay cedex, France Cardiovascular Institute and Fu Wai Heart Hospital, China Academy of Medical Sciences, Beijing 100037. School of Clinical Medicine, Bengbu Medical College, Bengbu 233000, China. Clinical Epidemiology Research Center, Peking University Third Hospital, Beijing 100083, China. Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei‐MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology Wuhan University Wuhan Hubei China; Department of Periodontology, School and Hospital of Stomatology Wuhan University Wuhan Hubei China Department of Respiratory Medicine, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou 310003, China. 159th Hospital, People's liberation Army. Department of Urology Fudan University Shanghai Cancer Center Shanghai China; Department of Oncology Fudan University Shanghai Medical College Shanghai China Department of Otorhinolaryngology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China. Department of Otorhinolaryngology Head and Neck Surgery, Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, Shandong Province, China. Department of Paediatrics, Shengjing Hospital of China Medical University, Shengyang, China Department of Pathology, Beijing Thorax Tumor and Tuberculosis Institute, Beijing 101149, China. Renal Research Institute, Sun Yat-sen University of Medical Sciences, Guangzhou. State Key Laboratory of Food Science and Technology Jiangnan University Wuxi P.R. China; School of Food Science and Technology Jiangnan University Wuxi P.R. China; National Engineering Research Center for Functional Food Jiangnan University Wuxi P.R. China; Wuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch Wuxi P.R. China Institute of Parasite Disease Prevention and Control Henan Center for Disease Prevention and Control Zhengzhou China Institute of Clinical Pharmacology, West China University of Medical Sciences, Chengdu. Department of Dermatology Peking Union Medical College Hospital Beijing China Biomaterials and Engineering Center, Wuhan University of Technology, PR China. zhhquan@yahoo.com Immunogenetics Laboratory Shenzhen Blood Center Shenzhen China KU Leuven 1 Department of Chemistry, , Leuven 3001, Belgium; IMEC 2 , Kapeldreef 75, 3001 Leuven, Belgium Department of Gastroentology, the Second Hospital of Hebei Medical University, Shijiazhuang 050035, China. |
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