http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_fd5d532cf229e3cdf0780a361c1093ec
Outgoing Links
| Predicate | Object |
|---|---|
| family-name | Yu Lei Yu |
| name | Lei Yu |
| given-name | Lei |
| organization-name | School of Chemistry and Chemical Engineering Yangzhou University Yangzhou 225002 China Jilin Radion and TV University; Changchun 130022; China Liver Cancer Institute Zhongshan Hospital Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University Shanghai China Shanghai Unicar-Therapy Bio-Medicine Technology Co., Ltd, Shanghai, China; Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China. *Institute of Immunology, School of Medicine, Zhejiang University, Hangzhou 310058, Zhejiang, China; and Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry Wuhan University Wuhan China Advanced Laboratory for Environmental Research & Technology, USTC-CityU, Suzhou 215123, China, State Key Laboratory in Marine Pollution, Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong SAR, China, and Department of Chemistry, University of Science & Technology of China, Hefei 230026, China Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, China. top1gods@email.ustc.edu.cn Department of Cardiac Surgery; the First Affiliated Hospital of China Medical University; Shenyang P.R. China Department of Neurological Sciences Rush University Chicago IL Prenatal Diagnosis Center Guizhou Medical University Guiyang, Guizhou China From the Rush Alzheimer's Disease Center (A.S.B., R.J.D., L.Y., R.S.W., J.A.S., D.A.B.), Department of Neurological Sciences (A.S.B., L.Y., R.S.W., J.A.S., D.A.B.), Department of Radiology (R.J.D.), Department of Psychology (R.S.W.), and Department of Pathology (Neuropathology) (J.A.S.), Rush University Medical Center Chicago, IL; and Department of Neurology (A.L.), University of Toronto, Ontario, Canada. China Animal Disease Control Center, Beijing 102618, China Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 9808575, Japan. DLH Corporation, Atlanta, GA; Rush University Medical Center Department of Neurological Sciences Rush Alzheimer's Disease Center Chicago Illinois USA Renal Division; Inner Mongolia People's Hospital; Hohhot People's Republic of China Center for Nanoscale Materials, Argonne National Laboratory, Lemont, Illinois 60439, United States Center for Nanoscale Materials, Argonne National Laboratory, Lemont, IL 60439, USA. From the *Department of Medical and Molecular Genetics, ‡Department of Microbiology and Immunology, §Department of Physiology and Biophysics, ‖Department of Medicine, and ¶Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202; and the **Department of Cell Biology, Neurobiology, and Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267; From the *Department of Medical and Molecular Genetics, ‡Department of Microbiology and Immunology, §Department of Physiology and Biophysics, ‖Department of Medicine, and ¶Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202; and the **Department of Cell Biology, Neurobiology, and Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 Authors' Affiliations: 1Liver Cancer Institute; 2Shanghai Key Laboratory of Organ Transplantation; 3Department of Pathology, Zhong Shan Hospital, Fudan University; and 4Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China Department of Physiology of The Guizhou Medical University, Guiyang 550004, Guizhou Province, China From the Rush Alzheimer's Disease Center (A.S.B., L.Y., R.S.W., J.A.S., D.A.B.), Departments of Neurological Sciences (A.S.B., L.Y., J.A.S., D.A.B.), Behavioral Sciences (R.S.W.), and Pathology (Neuropathology) (J.A.S.), Rush University Medical Center, Chicago, IL. Department of Chemistry and Biochemistry, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey, United States Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education, School of Energy and Environment, Southeast University, Nanjing 210096, China Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education); Department of Chemistry; Wuhan University; Wuhan 430072; P. R. China Key Laboratory of Atomic and Molecular Physics and Functional Materials of Gansu Province, College of Physics and Electronic Engineering, Northwest Normal University , Lanzhou 730070, China Department of Allergy and Otolaryngology The First Hospital of Hebei Medical University Shijiazhuang Hebei China College of Computer Science, Sichuan Normal University, Chengdu 610101, China Department of Botany and Plant Sciences, University of California, Riverside, CA, USA; Graduate Program in Genetics, Genomics, and Bioinformatics, University of California, Riverside, CA, USA Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products; National Institutes for Food and Drug Control; Beijing; China From Rush Alzheimer's Disease Center (A.S.B., S.E.L., L.Y., R.S.W., B.D.J., D.A.B.); Departments of Neurological Sciences (A.S.B., S.E.L., D.A.B.), Behavioral Sciences (R.S.W.), and Internal Medicine (B.D.J.), Rush University Medical Center, Chicago, IL; Department of Neurology (A.S.L.), University of Toronto, Canada; Departments of Neurology, Molecular and Human Genetics, Neuroscience, and Program in Developmental Biology (J.M.S.), Baylor College of Medicine; and Jan and Dan Duncan Neurological... Department of Traditional Chinese Medicine Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200065, P.R. China Department of Endocrinology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, P.R. China School of Environmental Science and Engineering, Hebei University of Science and Technology, Shijiazhuang, Hebei, China From the Department of Cardiac Surgery, China Medical University, The First Affiliated Hospital of China, Shenyang 110001, China Department of Chemistry, Oakland University, Rochester, Michigan 48309, and IL-TECH Inc., 69 Greenview Terrace, Middletown, Connecticut 06457 Department of Microbiology & Immunology Institute of Human Virology University of Maryland School of Medicine Baltimore MD USA Department of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States University of Chinese Academy of Sciences 19 Yuquan Road Beijing 100049 China; Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences 190 Kaiyuan Avenue, Guangzhou Science Park Guangzhou 510530 China Liver Cancer Institute, Zhongshan Hospital, Fudan University; People's Republic of China Departments of Pathology and Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA State Key Laboratory of Bio-Fibers and Eco-Textiles, Collaborative Innovation Center for Marine Biomass Fibers, Materials and Textiles of Shandong Province, College of Materials Science and Engineering, Insititute of Marine Biobased Materials, Qingdao University, Ningxia Road 308, Qingdao 266071, P.R. China Department of Pathophysiology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, Guizhou 550025, P.R. China Rush Alzheimer's Disease Center, Rush University Medical Center Chicago Illinois USA; Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA Rush Alzheimer Disease Center Rush University Medical Center Chicago Illinois USA; Department of Neurological Sciences Rush University Chicago Illinois USA Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Jiangsu Key Laboratory of Zoonosis, School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China From the Translational Neuroimaging Laboratory (A.L.B., S.M., T.A.P., M.S., M.-S.K., P.R.-N.), and Alzheimer's Disease Research Unit (S.G., P.R.-N.), McGill University Research Centre for Studies in Aging, Montreal, Canada; CAPES Foundation (A.L.B.), Ministry of Education of Brazil, Brasília, Brazil; Rush Alzheimer's Disease Center (L.Y., D.A.B.), Rush University Medical Center, Chicago, IL; Department of Decision Sciences (A.L.), HEC Montreal, Montreal, Canada; Department of Epidemiology (A.L.),... College of Veterinary Medicine; Northeast Agricultural University; Harbin; P. R. China Department of Basic Medicine, Xi'an Medical College, Xi'an, Shaanxi 710021, P.R. China Department of Cardiology, The Second Affiliated Hospital of Qiqihar Medical University Xiangya School of Medicine, Central South University, Changsha, Hunan Province, 410013, China Institute of Infectious Disease, Guangzhou Eighth People's Hospital, Guangzhou Medical University Guangzhou Guangdong China Soil and Fertilizer Station of Shandong Province Shandong Provincial Department of Agriculture Jinan China Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, United States; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, United States School of Stomatology, Weifang Medical University, Weifang 261053, Shandong, China Department of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai China; Department of Oncology Shanghai Medical College Fudan University Shanghai China State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China Rush Alzheimer’s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA Department of Orthopedics, The First Hospital of Qiqihaer, Qiqihaer, Heilongjiang 161005, P.R. China China Animal Disease Control Center, Beijing, China School of Life Sciences, Anhui University, Hefei 230601, China State Key Laboratory of Agricultural Microbiology Huazhong Agricultural University Wuhan 430070 China; Division of Animal Infectious Diseases in the State Key Laboratory of Agricultural Microbiology College of Veterinary Medicine Huazhong Agricultural University Wuhan 430070 China School of Materials Science and Engineering, National Institute for Advanced Materials, Nankai University, Tianjin 300350, China Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College (Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education), Beijing 100050, People’s Republic of China Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China School of Materials Science and Engineering, Tianjin Key Laboratory of Metal and Molecule-Based Material Chemistry, National Institute for Advanced Materials, Nankai University, Tianjin 300350, China School of Medical Laboratory Science, Guizhou Medical University, Guiyang, China. Key Laboratory of Mountain Surface Processes and Ecological Regulation, Institute of Mountain Hazards and Environment Chinese Academy of Sciences Chengdu 610041 China Department of Thoracic Surgery, Beijing Tongren Hospital Capital Medical University Beijing China Key Laboratory of Superlight Material and Surface Technology; Ministry of Education; Harbin Engineering University; , P. R. China From the Rush Alzheimer's Disease Center (A.K., L.Y., P.A.B., L.L.B., D.A.B., J.A.S.), Department of Pathology (A.K., J.A.S.), Department of Neurological Sciences (L.Y., L.L.B., D.A.B., J.A.S.), and Department of Behavioral Sciences (P.A.B., L.L.B.), Rush University Medical Center, Chicago, IL. Department of Medicine, University of Washington Medical Center , Seattle, WA , USA Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA Shanghai Unicar‐Therapy Bio‐medicine Technology Co., Ltd Shanghai China; Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University Shanghai China Department of Gynecology and Obstetrics, Guiyang Maternal and Child Health Hospital, Guiyang, Guizhou 550003, China Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois USA; Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Japan Department of Radiotherapy, The Second Hospital of Jilin University, Changchun, China Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, iChEM, Fudan University, Shanghai 200433, China Chinese Academy of Sciences Rush Alzheimer’s Disease Center Rush University Medical Center Chicago IL USA; Department of Neurological Sciences Rush University Medical Center Chicago IL USA From the Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada (A.S.P.L.); Department of Neurological Sciences, Rush Alzheimer’s Disease Center (L.Y., J.A.S., D.A.B., A.S.B.) and Department of Pathology (J.A.S.), Rush University, Chicago, IL. University of Sheffield School of Architecture, , Western Bank, Sheffield S10 2TN, United Kingdom Tongji University Cancer Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200092, China Department of Physiology, College of Basic Medical Sciences, Jilin University, Changchun, China Liver Cancer Laboratory, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China University of California, Riverside, USA The State Key Laboratory of Refractories and Metallurgy, the Institute of Advanced Materials and Nanotechnology, Wuhan University of Science and Technology, Wuhan, Hubei 430081, China Rush Alzheimer Disease Center (L.Y., J.A.S., D.A.B., A.S.B.), Rush University, Chicago, IL. Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China From the Rush Alzheimer's Disease Center (A.S.B., L.Y., P.A.B., J.A.S., D.A.B.), Neurological Science (A.S.B., L.Y., J.A.S., D.A.B.), Behavioral Sciences (P.A.B.), Pathology (Neuropathology) (J.A.S.), Rush University Medical Center, Chicago, IL; Program in Translational NeuroPsychiatric Genomics (P.L.D.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston; Harvard Medical School (P.L.D.), Boston; and Program in Medical and Population... College of Bioinformatics Science and Technology, Harbin Medical University Harbin Heilongjiang China Institute of Biomedical Engineering College of Life Science Qingdao University Qingdao 266071 P. R. China Key Laboratory of Human Disease Comparative Medicine, National Health Commission of China (NHC) Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences, Peking Union Medicine College Beijing China; National Human Diseases Animal Model Resource Center and Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences Beijing China School of Materials Science and Engineering National Institute for Advanced Materials Nankai University Tianjin 300350 China State Key Lab of Marine Resource Utilization in South China Sea; Hainan University; Haikou 570228; China Department of Thoracic Surgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China. Washington State Department of Agriculture, Pesticide Residue Laboratory, 2017 S. First St, Yakima, WA 98903 School of Basic Medical Sciences, North China University of Science and Technology, Tangshan, Hebei 063210, P.R. China Key Laboratory for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Nanjing 210094, People’s Republic of China Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois; Department of Neurological Sciences Rush University Medical Center Chicago Illinois the First Hospital of Peking University, Peking University Institute of Nephrology, Beijing, China. Department of the Orthopedics The First Affiliated Hospital of Zhengzhou University Zhengzhou China From the Rush Alzheimer's Disease Center (S.N., L.Y., R.S.W., E.-Y.C., D.A.B., J.A.S.) and Departments of Neurological Sciences (L.Y., R.S.W., D.A.B., J.A.S.), Behavioral Sciences (R.S.W.), and Pathology (Neuropathology) (S.N., J.A.S.), Rush University Medical Center, Chicago, IL. Prenatal Diagnostic Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China Tianjin Lonwin Technology Development Co., Ltd, No. 15 Longtan Road, Hedong District, Tianjin, China Australian Institute for Bioengineering and Nanotechnology The University of Queensland St Lucia QLD 4072 Australia Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL USA; Department of Neurological Sciences Rush University Medical Center Chicago IL USA School of Chemistry and Molecular Engineering East China Normal University Shanghai China; Shanghai Unicar‐Therapy Bio‐Medicine Technology Co., Ltd. Shanghai China Rush Alzheimer Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences; Rush University, Chicago, IL, USA. Department of Environmental and Occupational Health, Dongguan Key Laboratory of Environmental Medicine, School of Public Health Guangdong Medical University Dongguan China Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, United States Department of Biochemistry and Chemistry, The Ohio State University, Columbus, Ohio 43210, Department of Chemistry, Oakland University, Rochester, Michigan 48309, and Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China College of Chemistry & Chemical and Environmental Engineering, Weifang University, Weifang 261061, China Australian Institute for Bioengineering and Nanotechnology The University of Queensland St. Lucia Queensland 4072 Australia Laboratory of Cancer Epigenetics Department of Medical Oncology Biomedical Research Center Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou China From the Department of Pediatrics, NorthShore University Health Systems, Evanston, IL (A.D., M.D., K.L., L.Y., S.T.); Rehabilitation Institute of Chicago and Northwestern University, Chicago, IL (L.-Q.Z., Y.-N.W.); and the Laboratory of Neurosciences, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil (S.H.T.). Department of Colorectal Cancer Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People's Republic of China; Colorectal Cancer Institute of Harbin Medical University, Harbin, Heilongjiang, People's Republic of China Chemical Sciences and Engineering Division, Argonne National Laboratory, 9700 South Cass Avenue, Lemont, Illinois 60439, United States Institute of Biomedical Engineering and Technology Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development School of Chemistry and Molecular Engineering East China Normal University Shanghai China College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, People’s Republic of China Innovative Transportation Research Institute, Texas Southern University, Houston, TX, USA Key Laboratory of Human Disease Comparative Medicine NHFPC Institute of Laboratory Animal Science Peking Union Medicine College Chinese Academy of Medical Sciences Beijing China Department of Orthopedic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China Department of Chemistry, Clemson University, Clemson, South Carolina, 29634, and Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, E-28040 Madrid, Spain Department of Radiotherapy The Second Hospital of Jilin University Changchun 130041 China Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China Department of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai China; Department of Oncology, Shanghai Medical College Fudan University Shanghai China; Shanghai Clinical Research Center for Radiation Oncology Shanghai China; Shanghai Key Laboratory of Radiation Oncology Shanghai China Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL; Department of Neurological Sciences, Rush University, Chicago, IL College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, Shandong 266109, People’s Republic of China Department of Integrated Traditional Chinese Medicine and Western Medicine, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430016, Hubei, China. School of Pharmaceutical Sciences, Gannan Medical University, Ganzhou, 341000, China From the Department of Geriatrics (J.M.F.), University of Sao Paulo Medical School, Brazil; Department of Pathology (J.M.F., J.A.S.), Rush Alzheimer's Disease Center (J.M.F., L.Y., A.S.B., J.A.S., D.A.B.), and Department of Neurological Sciences (L.Y., A.S.B., J.A.S., D.A.B.), Rush University Medical Center, Chicago, IL; Program in Translational NeuroPsychiatric Genomics (P.L.D.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston; Harvard... Department of General Interventional Radiology, Guangxi Academy of Medical Sciences and The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi Zhuang Autonomous Region 530021, P.R. China 3Department of Pathophysiology, School of Medicine, Jinan University, Guangzhou 510632, China Department of Cardiology, the Third Hospital of Jinan, Shandong, China. Institute of Biomedical Engineering College of Life Sciences Qingdao University Qingdao 266071 China Department of Chemistry, Oakland University, Rochester, Michigan 48309, and Department of Biochemistry and Chemistry, The Ohio State University, Columbus, Ohio 43210 Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Fudan University, Ministry of Education, Shanghai 200032, P.R. China Prenatal Diagnosis Center, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China Institute of Immunology Zhejiang University School of Medicine Hangzhou China Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. From the Rush Alzheimer's Disease Center (A.S.B., L.Y., P.A.B., S.N., J.A.S., D.A.B.), Neurological Sciences (A.S.B., L.Y., D.A.B.), Behavioral Science (P.A.B.), and Pathology (S.N., J.A.S.), Rush University Medical Center, Chicago, IL; and Departments of Neurology (Stroke Center) and Emergency Medicine (S.R.L.), SUNY Downstate Medical Center, Brooklyn, NY. State Key Laboratory of Traditional Chinese Medicine Resources in Southwest China, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109;; Department of Cell & Developmental Biology, University of Michigan Medical Center, Ann Arbor, MI 48109; From the Department of Cardiac Surgery, The First Affiliated Hospital of China Medical University, Shenyang, China Bioproduct Research and Development, Lilly Research Laboratories, Eli Lilly and Company Department of Comprehensive Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences Wuhan University Wuhan Hubei China Key Laboratory of Southwestern Chinese Medicine Resources Chengdu University of Traditional Chinese Medicine Chengdu China Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois. Department of Pharmacy, The Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine, Hohhot, Inner Mongolia Autonomous Region 010020, P.R. China Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin 150001, Heilongjiang, China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry & Molecular Engineering, Peking University, Beijing 100871, P. R. China, Department of Molecular Biology, Beijing Institute of Transfusion Medicine, Beijing 100850, P. R. China, and Nitto Denko Technical Corporation, 501 Via Del Monte, Oceanside, California 92010 College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses; School of Chemistry and Chemical Engineering; Yangzhou University; Yangzhou; China State Key Laboratory of Pharmaceutical Biotechnology and Department of Biological Science and Technology, School of Life Sciences, Nanjing University, Nanjing, China Key Laboratory of Molecular Nanostructure and Nanotechnology and Beijing National Laboratory for Molecular Sciences; Institute of Chemistry; Chinese Academy of Sciences (CAS); Beijing 100190; P. R. China Liver Cancer Laboratory Department of Surgery Xiangya Hospital Central South University Changsha China Key Lab for Material Chemistry of Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, and National Anti-Counterfeit Engineering Research Center, Huazhong University of Science and Technology (HUST), Wuhan 430074, China Rush Alzheimer’s Disease Center, Chicago, IL, USA Department of Cardiac Surgery, The First Affiliated Hospital, China Medical University, Shenyang, China 110001 Department of Comprehensive Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Chemistry and Biochemistry, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028, United States School of Pharmacy, State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China College of Food science and Engineering Jilin Agricultural University Changchun China Rush Alzheimer’s Disease Center; Neurological Sciences Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, College of Material, Chemistry, and Chemical Engineering, Hangzhou Normal University, Hangzhou 311121, China Anhui Institute of Optics and Fine Mechanics Shanghai Unicar‐Therapy Bio‐medicine Technology Co. Ltd. Shanghai China From the Taub Institute for Research on Alzheimer's Disease and the Aging Brain (B.N.V., G.T., R. Lefort, P.L.D.J., S.B., D.R.-D., J.H.L., R.C., R. Lantigua, R.M.); Gertrude H. Sergievsky Center (B.N.V., G.T., S.B., D.R.-D., J.H.L., R.C., R.M.); Department of Neurology (P.L.D.J., S.B., R.M.), Department of Psychiatry (R.M.), Department of Systems Biology (B.N.V.), Department of Medicine (R. Lantigua), and Department of Pathology and Cell Biology (R. Lefort, P.L.N.), College of Physicians and... Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois. Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, PR China Department of Neurological Sciences Rush University Medical Center Chicago IL From the Department of Cardiology (X.H., Y.X., Z.Z., Y. Wu, J. Zhao, Yingchao Wang, J.J., Qingju Li, L.C., C.W., Y.F., R.W., J. L., J.Zhu, Ya Wang, Y.J., Y.L., F.Y., L.J., W.Z., J.C., H.Y., J.W.), Department of Cardiovascular Surgery (H.C., M.K.), Department of Anesthesiology (F.Z., Q.C.), Department of Radiology, (J.S., Qian Li), Department of Nuclear Medicine (H.Z.), and Department of Ultrasonography (Q.Y., L.Y.), Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou,... CT Department, Medical Imaging Center, Shandong Provincial Third Hospital, Jinan, Shandong 250031, P.R. China Research Division of Clinical Pharmacology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China Department of Pharmacy, Traditional Chinese Medicine Hospital of Inner Mongolia Autonomous Region, Hohhot, Inner Mongolia Autonomous Region 010020, P.R. China Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, China Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical college, Beijing, China. Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA Complex Systems Research Center, Shanxi University, Taiyuan 030006, P.R.China;Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163, P.R.China.yulei@sxu.edu.cn. Rush University Medical Center, Rush Alzheimer’s Disease Center, Chicago, IL 60612, USA. Department of Anatomy Key Laboratory of Construction and Detection of Guangdong Province Southern Medical University Guangzhou China Department of Urology, the First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, P.R. China; Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States Departments of Intervention Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL USA Rush Alzheimer's Disease Center & Department of Neurological Sciences Rush University Medical Center Chicago Illinois USA Department of Cell and Developmental Biology; From the Rush Alzheimer's Disease Center (R.S.W., T.W., L.Y., F.G., D.A.B., P.A.B.), Department of Neurological Sciences (R.S.W., T.W., L.Y., F.G., D.A.B.), and Department of Psychiatry and Behavioral Sciences (R.S.W., P.A.B.), Rush University Medical Center, Chicago, IL. Department of Thoracic Surgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China. Yulei1118@sohu.com Department of Biopharmaceutical Sciences College of Pharmacy, Harbin Medical University (Daqing) Daqing China Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P. R. China Prenatal Diagnostic Center, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, Guizhou, China School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China; Shanghai Unicar-Therapy Bio-medicine Technology Co., Ltd, Shanghai, China Beijing National Laboratory for Molecular Sciences, Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China Soochow University College of Chemistry, Chemical Engineering and Materials Science CHINA Affiliated Wuxi People's Hospital of Nanjing Medical University Wuxi Children's Hospital Wuxi Jiangsu China College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China Department of Orthopedics Department of Thoracic Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100069, China. Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Handan Road 220, Shanghai 200433, P. R. China 1Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI; 2Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI Research Center for Pharmacology and Toxicology, Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College Beijing People's Republic of China Department of Chemical and Biomolecular Engineering, University of Connecticut, 191 Auditorium Road, Unit 3222, Storrs, Connecticut 06269-4602, United States Department of Cardiology, Wujin Hospital affiliated with Jiangsu University, Changzhou, Jiangsu 213016, China Department of Physics and Astronomy and Biomedical Engineering Department, Tufts University, Medford, Massachusetts 02155 Wuhan Red Cross Hospital, Wuhan, Hubei 430000, China Nitto Denko Technical Corporation, Oceanside, California Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois 60612 Center for Nanoscale Materials, Argonne National Laboratory, Argonne, Illinois 60439, United States; Key Laboratory for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Nanjing 210094, China Department of Urology, Xijing Hospital Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China; School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang Province, China University of Chinese Academy of Sciences Shandong Agricultural University National Key Laboratory of Crop Biology, College of Horticulture Science and Engineering, , Tai’an, Shandong 271018, China for the Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Genetics Consortium, and Alzheimer’s Disease Sequencing Project International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development, Ministry of Education (MOE) of PR China, College of Pharmacy, Jinan University, Guangzhou 510632, China Harbin Engineering University School of Materials Engineering Changshu Institute of Technology Changshu 215500 China Department of Ophthalmology, Xi'an Fourth Municipal People's Hospital, Xi'an 710004, Shaanxi Province, China. Department of Surgery, Teikyo University, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan; Department of General Surgery, the 2nd Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang, Harbin, Heilongjiang 150086, China Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China Department of Chemistry and Key Laboratory of Organic Synthesis of Jiangsu Province, Soochow University, Suzhou 215123, People’s Republic of China, and State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, People’s Republic of China Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois 60612 IBM Research, Yorktown Heights, NY, USA 1Department of Endocrinology, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, China Xiamen Ocean Vocational College, Xiamen 361102, China Department of Orthopedics The First Affiliated Hospital of Zhengzhou University Zhengzhou China Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China. top1gods@email.ustc.edu.cn Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China Key State Laboratory of Fine Chemicals, School of Bioengineering, Dalian University of Technology, No. 2, Linggong Road, High-Tech District, Dalian 116024, P. R. China Department of Urology, Xijing Hospital Fourth Military Medical University Xi'an China Department of Otorhinolaryngology, The Second Hospital of Hebei Medical University, Shijiazhuang, China Tsinghua University Division of Advanced Manufacturing, Graduate School at Shenzhen, , Shenzhen 518055, China State Key Laboratory of Coordination Chemistry, MOE Key Laboratory of High Performance Polymer Materials and Technology, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA School of Pharmacy, Harbin University of Commerce, Harbin, China; Engineering Research Center of Natural Anticancer Drugs, Ministry of Education, Harbin, China Key Laboratory for Soft Chemistry and Functional Materials School of Chemistry and Chemical Engineering School of Energy and Power Engineering Nanjing University of Science and Technology Nanjing 210094 China Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China; Zhejiang Key Laboratory of Carbon Materials, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035, China Department of Thoracic Surgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China. yulei1118@sohu.com College of Chemistry; Chemical Engineering and Materials Science; Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong; Key Laboratory of MoleCular and Nano Probes; Ministry of Education Department of Clinical Laboratory, Wuhan City No. 3 Hospital Wuhan 430060, Hubei, China. Department of Urology, Xi-jing Hospital, the Fourth Military Medical University Department of Genetics, Center of Alcohol Studies, Rutgers University, Piscataway, NJ, USA Information Technology Department, Shanghai Sixth People's Hospital, Shanghai, China Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois Department of Orthopedics The First Affiliated Hospital of Soochow University 188 Shizi Road Suzhou Jiangsu 215006 China Department of Environmental Engineering, Nanjing Forestry University, Nanjing, China Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry, Wuhan University, Wuhan 430072, P.R. China Research and Development Division, Educational Testing Service, Rosedale Road, MS 15-L, Princeton, NJ 08541, USA. lyu@ets.org Contribution from the Department of Chemistry, Clemson University, Clemson, South Carolina 29634 From the Rush Alzheimer's Disease Center (A.S.B., L.Y., R.S.W., R.J.D., C.G., S.E.L., J.A.S., D.A.B.), and Departments of Neurological Sciences (A.S.B., L.Y., R.S.W., C.G., S.E.L., J.A.S., D.A.B.), Radiology (R.J.D.), Psychology (R.S.W.), and Pathology (Neuropathology) (J.A.S.), Rush University Medical Center, Chicago, IL; and Department of Neurology (A.L.), University of Toronto, Canada. Department of Neurology, Dalian Friendship Hospital, Dalian City, Liaoning, China Department of Medical and Molecular Genetics, Indiana University School of Medicine Neurogenetics and Integrated Genomics Andover Innovative Medicines Institute, Eisai Inc Andover MA USA; Department of Medicine (Biomedical Genetics) Boston University Schools of Medicine Boston MA USA; Department of Neurology Boston University Schools of Medicine Boston MA USA; Department of Pharmacology and Neuroscience University of North Texas Health Science Center Fort Worth TX USA; The John P. Hussman Institute for Human Genomics University of Miami Miami FL USA Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois Key Laboratory of Human Disease Comparative Medicine National Health Commission of China (NHC) Institute of Laboratory Animal Science Peking Union Medicine College Chinese Academy of Medical Sciences Beijing China; Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases Institute of Laboratory Animal Science Peking Union Medicine College Chinese Academy of Medical Sciences Beijing China Institute of Microbiology, College of Life Sciences Zhejiang University Hangzhou China Department of Infectious Disease, the Fourth Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China. Department of Biology, Georgia State University, Atlanta, Georgia From Rush Alzheimer's Disease Center and Departments of Neurological Sciences (R.S.W., L.Y., L.L.B., A.S.B., D.A.B., J.A.S.), Behavioral Sciences (R.S.W., P.A.B., L.L.B.), and Pathology (J.A.S.), Rush University Medical Center, Chicago, IL. State Key Laboratory of Crop Biology, College of Horticulture Science and Engineering, Shandong Agricultural University, Tai’an, Shandong 271018, People’s Republic of China; Collaborative Innovation Center of Fruit & Vegetable Quality and Efficient Production, Tai’an, Shandong 271000, People’s Republic of China Department of Cardiac Surgery The First Hospital of China Medical University Shenyang 110001 China State Key Laboratory of Coordination Chemistry; Jiangsu Key Laboratory of Advanced Organic Materials; Collaborative Innovation Center of Advanced Microstructures; School of Chemistry and Chemical Engineering; Nanjing University Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China. top1gods@email.ustc.edu.cn Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL Jiangsu Key Laboratory of Chiral Pharmaceuticals Biosynthesis, Taizhou University, Taizhou 225300, China State Key Laboratory of Pharmaceutical Biotechnology Department of Biological Science and Technology School of Life Sciences Nanjing University Nanjing China Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering Southern Medical University Guangzhou Guangdong 510515 P. R. China Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois USA Shanghai Unicar‐Therapy Bio‐medicine Technology Co., Ltd. Shanghai China; Institute of Biomedical Engineering and Technology Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development School of Chemistry and Molecular Engineering East China Normal University Shanghai China Center for Nanomaterials, Argonne National Laboratory, 9700 South Cass Avenue, Lemont, Illinois 60439, United States School of Chemistry and Materials Science, Jiangsu Normal University Department of Pediatrics, NorthShore University HealthSystem Evanston and University of Chicago Chicago Illinois USA Cell and Development Biology, University of Michigan Department of Infectious Disease, The Fourth Hospital of Harbin Medical University Harbin 150001, Heilongjiang, China. Guangzhou 8th People’s Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China Zhejiang Key Laboratory of Carbon Materials, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035, China; School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China; Davenport Chemistry Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada Center of Research and Development on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin, Heilongjiang�150076, P.R. China College of Veterinary Medicine Nanjing Agricultural University Nanjing People's Republic of China; Key Laboratory of Animal Physiology and Biochemistry Ministry of Agriculture Nanjing People's Republic of China Shanghai Unicar-Therapy Bio-medicine Technology Co., Ltd, Shanghai, PR China;; School of Chemistry and Molecular Engineering, East China Normal University, Suzhou, PR China; School of Agriculture and Biotechnology, Kunming University, Kunming, Yunnan, China Department of Chemistry and Biochemistry, Rowan University, Glassboro, New Jersey 08028 Department of Epidemiology, College of Preventive Medicine, Third Military Medical University Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois (P.A.B., L.Y., J.A.S., R.S.W., D.A.B.) Department of Radiology, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China Department of Urology, Xijing Hospital, the Fourth Military Medical University , Xi'an, China Department of Orthopedics, The First Affiliated Hospital of Soochow University , No. 188 Shizi Street , Suzhou 215000, China Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, China Shandong Jiaotong University, No. 5001 Haitang Road, Changqing District, Jinan 250357, China Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, P.R. China Department of Dermatology, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong 510282, P.R. China Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, People’s Republic of China Division of Infection Disease Zhejiang Key Laboratory for Neonatal Diseases Children Hospital Zhejiang University School of Medicine Hangzhou China; Laboratory of Cancer Biology Sir Runrun Shaw Hospital Zhejiang University School of Medicine Hangzhou China Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China From the Rush Alzheimer’s Disease Center (L.Y., P.A.B., R.S.W., J.A.S., D.A.B.), Department of Neurological Sciences (L.Y., R.S.W., J.A.S., D.A.B.), Department of Behavioral Sciences (P.A.B., R.S.W.), and Department of Pathology (J.A.S.), Rush University Medical Center, Chicago, IL; Department of Neurology and Emergency Medicine, State University of New York Downstate Medical Center, Brooklyn (S.R.L.); and Department of Neurology, Kings County Hospital Center, Brooklyn, NY (S.R.L.). Department of Chemistry University of Kentucky Lexington KY 40506 USA Operation Department Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China From the Departments of Neurological Sciences (R.S.W., L.Y., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., M.L., P.A.B.), and Pathology (J.A.S.), Rush University Medical Center, Rush Alzheimer's Disease Center, Chicago, IL. Innovative Transportation Research Institute, Texas Southern University, Houston, TX, USA; Xuchang University, College of Transportation, Xuchang City, Henan Province, People’s Republic of China Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI; Department of Cardiac Surgery; The First Affiliated Hospital of China Medical University; Shenyang P. R. China Free Radical & Radiation Biology Graduate Program, Radiation Oncology Department, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA School of Medicine and Life SciencesNanjing University of Chinese Medicine Nanjing China; Key Laboratory of Chinese Medicine for Prevention and Treatment of Neurological DiseasesNanjing University of Chinese Medicine Nanjing China Department of General Surgery, First Affiliated Hospital of China Medical University, Shenyang Liaoning, P.R. China Guangdong Key Laboratory of Systems Biology and Synthetic Biology for Urogenital Tumors Shenzhen 518035 China; Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China Life Sciences Institute, University of Michigan Medical Center, Ann Arbor, Michigan; Department of Cell and Developmental Biology, University of Michigan Medical Center, Ann Arbor, Michigan Department of Forensic Medicine, Sun Yat-sen Medical College, Sun Yat-sen University, Guangzhou 510089, China. Department of Medicine, Division of Gastroenterology, University of Washington School of Medicine Seattle Washington University of Washington, Seattle, Washington, USA College of Science, Engineering and Technology, Texas Southern University, Houston, TX, USA Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering East China Normal University Shanghai China Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202-5251; Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0521; and Laboratory on the Biology of Addictive Diseases and Laboratory of Statistical Genetics, The Rockefeller University, New York, NY 10021-6399 Key Laboratory of Southwestern Chinese Medicine Resources School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu China Department of Neurosurgery Harbin Medical University Cancer Hospital Harbin Heilongjiang China Department of Pediatrics,2 Center for Molecular Genetics, University of California—San Diego, La Jolla, California 92093-0634 Department of Echocardiography The Second Affiliated Hospital, Zhejiang University School of Medicine Hangzhou China 3Shanghai Unicar-Therapy Bio-Medicine Technology Co, Ltd, Shanghai, China; 5Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China Department of Biopharmaceutical Sciences, College of Pharmacy, Harbin Medical University, Daqing, PR China; Rush Alzheimer Disease Center and Department of Neurological Sciences, Rush University, Chicago, IL Key Laboratory of Human Disease Comparative Medicine Institute of Laboratory Animal Science Chinese Academy of Medical Sciences Beijing China Department of Dermatology, Zhujiang Hospital of Southern Medical University, No. 253 Gongye Avenue, Guangzhou 510091, People's Republic of China Institute of Strategic Planning, Chinese Academy of Environmental Planning, Ministry of Ecology and Environment, Beijing 100012, China Key Laboratory for Chinese Medicine of Prevention and Treatment in Neurological Diseases, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023 Jiangsu, China; School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, 210023 Jiangsu, China Department of Pathology Guiyang Maternal and Child Health Hospital Guiyang Guizhou China Jian Zhou, Lei Yu, Jie Hu, Zhi Dai, Xiaowu Huang, Zheng Wang, Shuangjian Qiu, Xiaoying Wang, Guohuan Yang, Huichuan Sun, Zhaoyou Tang, and Jia Fan, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Jian Zhou, Xue Gao, Hongguang Zhu, and Jia Fan, Institute of Biomedical Sciences, Fudan University; Jie-Fei Wang, Zhiyong Zhang, Shanghai Public Health Clinic Center; Shaohua Lu, Zhongshan Hospital, Fudan University; Ying Wu and Hongguang Zhu, Shanghai Medical College, Fudan University, Shanghai,... Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry, Wuhan University, Wuhan, Hubei 430072, People’s Republic of China School of Chemistry and Materials Science Jiangsu Normal University 221116 Xuzhou China Research Center on Life Sciences and Environmental Sciences, Harbin University of Commerce Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China. top1gods@mail.ustc.edu.cn Miami University, Oxford, OH, USA State Key Laboratory of Bio‐Fibers and Eco‐Textiles Collaborative Innovation Center for Marine Biomass Fibers Materials and Textiles of Shandong Province College of Materials Science and Engineering Institute of Marine Biobased Materials Qingdao University Ningxia Road 308 Qingdao 266071 P. R. China Department of Urology, The Affiliated Suqian First People’s Hospital of Nanjing Medical University, Suqian, China; Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, P.R. China 1Department of Cell and Developmental Biology, Department of Chemistry, Oakland University, Rochester, Michigan 48309 Guangxi Zhuang Autonomous Region Terrestrial Wildlife Medical-aid and Monitoring Epidemic Diseases Research Center, Nanning, P.R. People’s Republic of China College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China From the Departments of Neurological Sciences (R.S.W., L.Y., S.E.L., D.A.B.) and Behavioral Sciences (R.S.W., P.A.B.), Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL. Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou 311121, China Email: fengyun7612@163.com. School of Pharmacy, Wenzhou Medical University, Wenzhou 325035, China College of Agriculture and Life Sciences, Yunnan Urban Agricultural Engineering & Technological Research Center, Kunming University Kunming, China Department of Transportation Studies, Texas Southern University, Houston, TX, USA; College of Traffic and Transportation, Beijing Jiaotong University, Beijing, China Center for Nanoscale Materials Argonne National Laboratory Lemont IL 60439 USA Department of Medical and Molecular Genetics, Indiana University of Medicine University of Sheffield School of Architecture, , Western Bank, Sheffield, S10 2TN, United Kingdom School of Chemistry & Chemical Engineering and Environmental Engineering Weifang University Weifang 261061, Shandong P.R. China Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL; Department of Neurological Sciences Rush University Medical Center Chicago IL Prenatal Diagnosis Center, Hospital Affiliated to Guizhou Medical University, Guiyang 550004, Guizhou, China Centre for Plant Integrative Biology, University of Nottingham, Nottingham LE12 5RD, United Kingdom Department of Psychology and Neuroscience Program, University of Illinois at Urbana-Champaign, Champaign, Illinois, 61820;; Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio, 45267;; Departments of Anatomy and Physiology, W.M. Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, California, 94143; Department of Orthopaedics Changzheng Hospital, Second Military Medical University Shanghai China From the Rush Alzheimer's Disease Center (L.Y., R.S.W., C.G., L.L.B., D.A.B.) and Department of Neurological Sciences (L.Y., R.S.W., C.G., L.L.B., D.A.B.), Rush University Medical Center, Chicago, IL; Department of Neurology (M.W.L., A.D.R., A.M.S.), Duke University School of Medicine, Durham; Zinfandel Pharmaceuticals, Inc (D.K.B., A.D.R.), Research Triangle Park, NC; Program in Translational NeuroPsychiatric Genomics (P.L.D.), Institute for the Neurosciences, Departments of Neurology and... Department of Infectious Disease, the Fourth Hospital of Harbin Medical University, Harbin, China Department of Forensic Medicine, Sun Yat-Sen University of Medical Sciences, Guangzhou, Guangdong, 510089 P.R.China. xyaow@gzsums.edu.cn Department of Chemistry State Key Laboratory of Molecular Engineering of Polymers Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials iChEM Fudan University Shanghai 200433 China The State Key Laboratory of Refractories and Metallurgy; and Institute of Advanced Materials and Nanotechnology; Wuhan University of Science and Technology; Wuhan 430081; China College of Population Resources and Environment Shandong Normal University Jinan 250014 People's Republic of China The Sixth Affiliated Hospital of Kunming Medical University, Yuxi School of Biology & Basic Medical Science, Soochow University, Suzhou, China Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences Guangzhou China From the Rush Alzheimer's Disease Center (L.Y., P.A.B., J.Y., T.W., A.S.B., J.A.S., D.A.B.), Department of Neurological Sciences (L.Y., J.Y., T.W., A.S.B., D.A.B.), Department of Psychiatry and Behavioral Sciences (P.A.B.), and Department of Pathology (J.A.S.), Rush University Medical Center, Chicago, IL; Division of Mental Health (A.P.W.), Atlanta VA Medical Center, Decatur; Departments of Psychiatry (A.P.W.), Neurology (T.S.W., A.I.L.), and Human Genetics (T.S.W.), Emory University School of... Infectious Disease, the Fourth Hospital of Harbin Medical University, Harbin, People's Republic of China; College of Agronomy, Yunnan Urban Agricultural Engineering and Technological Research Center, Kunming University, Kunming 650214, China Department of Cardiac Surgery, China Medical University, The First Affiliated Hospital, Shenyang, China Department of Interventional Radiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, PR China. Rush Alzheimer’s Disease Center, Rush University Medical Center , Chicago, Illinois , USA; Department of Neurological Sciences, Rush University Medical Center , Chicago, Illinois , USA Tianjin Lonwin Technology development Co., Ltd, No. 15 Longtan Road, Hedong District, Tianjin, China From the Rush Alzheimer's Disease Center (A.S.B., L.Y., R.S.W., S.E.L., S.N., L.L.B., J.A.S., D.A.B.), and Departments of Neurological Sciences (A.S.B., L.Y., R.S.W., S.E.L., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., L.L.B.), and Pathology (Neuropathology) (S.N., J.A.S.), Rush University Medical Center, Chicago, IL; Departments of Neurology, Molecular and Human Genetics, Neuroscience, and Program in Developmental Biology (J.M.S.), Baylor College of Medicine, Houston, TX; and Jan and Dan Duncan... Xi'an Medical CollegeXi'an 710021, Shaanxi, China. Department of Ultrasound, Peking University People’s Hospital, Beijing, People’s Republic of China. a Department of Transportation Studies , Texas Southern University , Houston , TX; d School of Traffic and Transportation , Beijing Jiaotong University , Beijing , People’s Republic of China Beijing Tongren Hospital, Capital Medical University, Beijing, China College of Communication & Information Engineering, Beijing University of Posts and Telecommunications, Beijing, 100876. Institute of Biomedical Engineering and Technology Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development School of Chemistry and Molecular Engineering East China Normal University Shanghai 200062 P. R. China Department of Biochemistry and Molecular Biology, School of Pre-Clinical Medicine, Guangxi Medical University, Nanning, 53002 Guangxi, China Department of Oncology, Jiangsu Taizhou People’s Hospital, Taizhou, China Rush Alzheimer’s Disease Center (S.O., L.Y., A.C., Z.A., L.L.B., J.A.S., D.A.B., A.S.B.), Rush University Medical Center, Chicago, IL.; Department of Neurological Sciences (S.O., L.Y., A.C., Z.A., L.L.B., J.A.S., D.A.B., A.S.B.), Rush University Medical Center, Chicago, IL. Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois. Liver Cancer Institute and Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion; Fudan University, Ministry of Education; Shanghai People's Republic of China Department of Thoracic Surgery, Peking University Shougang Hospital, Beijing 100144, P.R. China National Institute of AIDS/STD Control and Prevention, China CDC, Beijing 102206, China. Yunnan Urban Agricultural Engineering and Technological Research Center, College of Agronomy, Kunming University, Kunming, China Key Laboratory of Animal Physiology and Biochemistry College of Veterinary Medicine Nanjing Agricultural University Nanjing China Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America. Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic Materials School of Chemistry and Chemical Engineering Nanjing University Nanjing 210023 China Department of Thoracic Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China. yulei1118@sohu.com Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois2Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois Institute of Shenzhen Translational Medicine, Shenzhen Second People’s Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China State Key Laboratory of Crop Biology, College of Horticulture Sciences, Shandong Agricultural University, 271018 Tai’an, Shandong, China State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China Department of Neurosurgery, Harbin Medical University Cancer Hospital, Harbin 150001, Heilongjiang, China Department of Urology Xijing Hospital, The Fourth Military Medical University Xi'an Shaanxi P.R. China Department of Forensic Medicine, Sun Yat-sen Medical College, Sun Yat-sen University, Guangzhou 510080, China. Department of Interventional Radiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China. From the Rush Alzheimer's Disease Center (P.A.B., L.Y., S.N., S.L., R.S.W., D.A.B., J.A.S.) and Departments of Behavioral Sciences (P.A.B., R.S.W.), Neurological Sciences (L.Y., S.N., S.L., R.S.W., D.A.B., J.A.S.), and Pathology (S.N., J.A.S.), Rush University Medical Center, Chicago, IL. Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60614, USA Department of Oncology, Jiangsu Taizhou People's Hospital, Taizhou, Jiangsu 225300, P.R. China Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences, Beijing, China University of Nebraska Medical Center State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan 430072, China c Tianjin Lonwin Technology Development Co., Ltd, No. 15 Longtan Road, Hedong District, Tianjin, China State Key Laboratory of Crop Biology, College of Horticulture Science and Engineering Shandong Agricultural University Tai'an Shandong 271018 China; Collaborative Innovation Center of Fruit & Vegetable Quality and Efficient Production Tai'an Shandong 271000 China Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China. From the Departments of Pathology (Neuropathology) (S.N., J.A.S.), Neurological Sciences (L.L.B., L.Y., A.S.B., D.A.B., J.A.S., R.S.W.), and Psychiatry and Behavioral Sciences (L.L.B., R.S.W.), Rush Alzheimer Disease Center and Rush University Medical Center, Chicago, IL. Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China;; Shanghai Unicar-Therapy Bio-medicine Technology Co., Ltd, Shanghai, China; Shanghai Unicar-Therapy Biomed-Phamaceutical Technology Co., Shanghai 201203, China. Renal Division of First Hospital, Institute of Nephrology, Peking University, Beijing 100034, China. Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA. Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA. Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA; Neurological Sciences, Rush University Medical Center, Chicago, IL, USA State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, China University of Petroleum Beijing, Beijing 102249, China College of Forestry, Shenyang Agricultural University, Shenyang, Liaoning, China; Key Laboratory of Tree Genetics, Breeding and Cultivation in Liaoning Province, China, Shenyang, China School of Chemistry and Chemical Engineering, Yangzhou University, Shouxihu Campus, Yangzhou 225002, People’s Republic of China Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, Institute of Biomedical Engineering and Technology East China Normal University Shanghai China; Shanghai Unicar‐Therapy Bio‐medicine Technology Co., Ltd Shanghai China Bio Group, Nitto Denko Technical Corporation, Oceanside, California Key Laboratory of Animal Physiology and Biochemistry, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China Department of Infectious Disease, The Fourth Hospital of Harbin Medical University, Harbin 150001, China College of Materials Science and Engineering, Chongqing University, Chongqing 400044, China. From the Rush Alzheimer's Disease Center (L.Y., P.A.B., R.J.D., D.A.B., K.A., J.A.S.), Department of Neurological Sciences (L.Y., D.A.B., J.A.S.), Department of Behavioral Sciences (P.A.B.), Department of Diagnostic Radiology and Nuclear Medicine (R.J.D., K.A.), and Department of Pathology (J.A.S.), Rush University Medical Center; and Department of Biomedical Engineering (K.A.), Illinois Institute of Technology, Chicago. Department of Nephrology, Inner Mongolia People’s Hospital, Hohhot, China Department of Infectious Diseases, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, Arizona 85287-6106, United States Institute of Biomedical Engineering, College of Life Science, Basic Medical College, Qingdao University, Qingdao 266071, China From the Rush Alzheimer’s Disease Center (Z.A., J.A.S., A.W.C., L.Y., S.E.L., D.A.B.), Department of Neurological Sciences (Z.A., J.A.S., A.W.C., L.Y., S.E.L., D.A.B.), and Department of Pathology (J.A.S.), Rush University Medical Center, Chicago, IL; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio (R.L.B.); Department of Pathology, Montefiore Medical Center, Bronx, NY (J.H.R.); and Departments of Neurology and Emergency Medicine, State University of... From the Rush Alzheimer's Disease Center and Departments of Neurological Sciences (R.S.W., L.Y., L.L.B., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., P.A.B., L.L.B.), and Pathology (J.A.S.), Rush University Medical Center, Chicago, IL. Institute of Pesticide of School of Chemistry and Chemical Engineering and School of Horticulture and Plant Protection Yangzhou University Yangzhou Jiangsu 225002 China Laboratory of Cancer Epigenetics, Department of Medical Oncology, Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China Department of Cardiac Surgery, The First Affiliated Hospital of China Medical University, Shenyang 110001, People's Republic of China. Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, P. R. China Department of Spinal Surgery, Changzheng Hospital Second Military Medical University Shanghai China Liver Care & Transplantation Services, University of Washington Medical Center, Seattle, Washington. Critical Care Medical Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, P.R. China Department of Cardiac Surgery, the First Affiliated Hospital of China Medical University, Shenyang 110001, China. Department of Laboratory Medicine Affiliated Wuxi people's Hospital of Nanjing Medical University Wuxi China Anne A. Kimball, Weiming Zhu, Mary R. Tanner, Kashif Iqbal, Kenneth L. Dominguez, Kevin P. Delaney, and Karen W. Hoover are with the Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA. Lei Yu is with the DLH Corporation, Atlanta. Aparna Shankar is with the New York City Department of Health and Mental Hygiene, New York, NY. Kate Drezner is with the District of Columbia Department of Health, Washington, DC. Karen Musgrove is with Birmingham AIDS Outreach, Birmingham, AL.... Medicine, University of Washington, Seattle, WA Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China Department of Chemistry, Zhejiang University (Xixi Campus), Hangzhou 310028, People’s Republic of China, and State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, People’s Republic of China Rush Alzheimer's Disease Center; Departments of Neurological Sciences Departments of Chemistry and Biological Sciences, Oakland University, Rochester, Michigan 48309, and Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232 Prenatal Diagnosis Center, Hospital affiliated to Guizhou Medical University, Guiyang 550004, Guizhou, China From the Department of Cardiac Surgery, the First Affiliated Hospital of China Medical University, Shenyang, China Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, People’s Republic of China College of Chemistry and Molecular Engineering, East China Normal University School of Chemistry and Molecular Engineering, East China Normal University; Shanghai Unicar-Therapy Bio-medicine Technology Co. Ltd, Shanghai Department of Urology , Xi’an , China; Xijing Hospital , Xi’an , China; Fourth Military Medical University , Xi’an , China Department of Cardiac Surgery, China Medical University, Shenyang 110001, China. Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, Sichuan, China From the Program in Translational NeuroPsychiatric Genomics (T.R., L.B.C., J.M.R., P.L.D.J.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Center for Neurologic Disease (T.R., A.W., A.K., P.L.D.J.), Department of Neurology, and Division of Genetics (T.R., L.B.C., P.L.D.J.), Department of Medicine, Brigham and Women's Hospital, Boston, MA; Harvard Medical School (T.R., L.B.C., P.L.D.J.), Boston, MA; Program in Medical and Population genetics (T.R., L.B.C., C.M., J.M.R., P... State Key Laboratory of Pulsed Power Laser Technology, Hefei, Anhui, China; Anhui Province Key Laboratory of Electronic Restriction, Hefei, Anhui, China Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, P.R. China. State Key Laboratory of Heavy Oil Processing, China University of Petroleum, Changping, Beijing 102249, China Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangdong, Guangzhou 510515, China. Research Center of Chiral Functional Heterocycles, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou 221116, China Department of Medical Biochemistry, Graduate School of Medicine, Tohoku University, Sendai, Japan Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University , No, 3663 North Zhongshan Road, Shanghai 200065 , China; Shanghai Unicar-Therapy Bio-medicine Technology Co. , Ltd, No 1525 Minqiang Road, Shanghai, 201612 , China School of Chemistry and Chemical Engineering Yangzhou University Yangzhou Jiangsu 225002 China Jilin Radio and TV University; Changchun 130022; China College of Marine Biology, Xiamen Ocean Vocational College Department of Biological Science and Technology and State Key Laboratory of Pharmaceutical Biotechnology School of Life Sciences Nanjing University Nanjing China Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses; Yangzhou University; Yangzhou; China Department of Cardiac Surgery; The First Affiliated Hospital of China Medical University; Shenyang P.R. China From Rush Alzheimer's Disease Center (S.O., A.S.B., L.Y., J.F., C.G., J.A.S., D.A.B.) and Departments of Neurological Sciences (A.S.B., L.Y., J.A.S., D.A.B.) and Pathology (J.F., J.A.S.), Rush University Medical Center, Chicago, IL; Shariati Hospital (S.O.), Tehran University of Medical Sciences, Iran; Department of Geriatrics (J.F.), University of Sao Paulo Medical School, Brazil; University Hospital (V.H.), University of Western Ontario, London, Canada; Broad Institute (P.L.D.J.), Cambridge, MA;... Department of Urology The Affiliated Suqian First People's Hospital of Nanjing Medical University Suqian Jiangsu Province China Shanghai Unicar‐Therapy Bio‐medicine Technology Co., Ltd Shanghai China School of Biological and the Environmental, Nanjing Forestry University, Nanjing 210037, China. Dept. of Orthodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China. Department of Andrology Affiliated Hospital of Qingdao University Qingdao Shandong China Department of Chemistry, Oakland University, Rochester, Michigan 48309, and Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232 Institute of Biomedical Engineering, Technology, Shanghai Engineering Research Center of Molecular Therapeutics, New Drug Development, School of Chemistry, Molecular Engineering, East China Normal University, Shanghai 200062, China State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Peopleʼs Republic of China Rush Alzheimer's Disease Center; Department of Neurological Sciences Key Laboratory of Soft Matter Chemistry; Chinese Academy of Science; Department of Polymer Science and Engineering; University of Science and Technology of China; Hefei Department of Analytical and Formulation Sciences and †Systems Informatics, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, Jiangsu 210023, China; Key Laboratory of Chinese Medicine for Prevention and Treatment of Neurological Diseases, Nanjing University of Chinese Medicine, 138 Xianlin Rd, Nanjing, Jiangsu 210023, China; State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Drug Target and Drug for Degenerative Disease of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing 210023, China; Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China Rush Alzheimer’s Disease Center, Chicago, Illinois From the Rush Alzheimer's Disease Center (L.Y., J.Y., D.A.B., J.A.S.), the Department of Neurological Sciences (L.Y., J.Y., D.A.B., J.A.S.), and the Department of Pathology (J.A.S.), Rush University Medical Center, Chicago, IL; Program in Translational NeuroPsychiatric Genomics (P.L.D.), Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston; Harvard Medical School (P.L.D.), Boston; Program in Medical and Population Genetics, Broad Institute (P... Department of Otorhinolaryngology, The Second Hospital of Hebei Medical University , Shijiazhuang , Hebei , China MOE Key Laboratory for Urban Transportation Complex Systems Theory and Technology, School of Traffic and Transportation, Beijing Jiaotong University, Beijing, People’s Republic of China; College of Science, Engineering and Technology, Texas Southern University, Houston, TX, USA Institute of Physical Education, Jiangsu Second Normal University, Nanjing, China Department of Echocardiography,Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China. Department of Biology, Georgia State University, Atlanta, Georgia; and; School of Pharmacy, Harbin Medical University, Harbin, Heilongjiang, China Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland) Department of Intensive Care Unit, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China. Corresponding author: Sun Rongqing, Email: rongqing.sun@126.com. From the Rush Alzheimer's Disease Center and Departments of Neurological Sciences (R.S.W., L.Y., A.S.B., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., P.A.B.), and Pathology (S.N., J.A.S.), Rush University Medical Center (L.P.H.), Chicago, IL. Department of Echocardiography, The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China Center for Nanoscale Materials, Argonne National Laboratory, 9700 South Cass Avenue, Lemont, Illinois 60439, United States Rush University Medical Center, Rush Alzheimer’s Disease Center, Chicago, IL 60612, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA Department of Plastic Surgery, the Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University Department of Urology, First Hospital of Harbin, Harbin 150010, China. yuleidoctor@yahoo.com.cn Thoracic Surgery China Animal Disease Control Center, Tiangui Street No. 17, Daxing District, Beijing 102600, China Rush University Medical Center, Chicago, IL, USA College of Agriculture and Life Sciences, Yunnan Urban Agricultural Engineering & Technological Research Centre, Kunming University, Kunming China College of Life and Environmental Sciences Hangzhou Normal University Hangzhou 310036 Zhejiang China State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China; Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences, Qingdao 266101, P. R. China Department of Ecology, College of Life and Environmental Sciences, Hangzhou Normal University, Yuhangtang Road 2318, Hangzhou 311121, China Biomedical Engineering and Technology Institute, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 N. Zhongshan Rd., Shanghai 200062, PR China Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China Medical and Population Genetics Broad Institute of MIT and Harvard Cambridge Massachusetts 02142; Rush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois 60612 Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA Department of Cardiology Jinan Third People's Hospital Jinan China Center for Nanoscale Materials Argonne National Laboratory Argonne IL 60439 USA Division of Life Science, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, China. Beijing National Laboratory for Molecular Sciences (BNLMS); Laboratory of Polymer Physics and Chemistry; Institute of Chemistry; Chinese Academy of Sciences; Beijing 100190 School of Chemistry, Monash University, Clayton, Victoria 3800, Australia Key Laboratory of Tropical Biological Resources of Ministry of Education; Hainan University; Haikou 570228; China VTT Biotechnology, Technical Research Centre of Finland, PO Box 1000, FI-02044 VTT, Finland; College of Life Sciences, Nankai University, No. 94 Weijin Road, Tianjin 300071, PR China Center for Nanoscale Materials, Argonne National Laboratory, Lemont, IL 60439 Department of Medical Biochemistry and Department of Pharmacy, Traditional Chinese Medicine Hospital of Inner Mongolia Autonomous Region Hohhot 010020, Inner Mongolia Autonomous Region, China. Department of Neurological Sciences Rush University Medical Center Chicago IL 60612 USA Cancer Center, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. Department of Radiology, Shandong Provincial Third Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences 1Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai, China. Department of Pharmacy, West China Hospital Sichuan University Chengdu Sichuan China Bioinformatics at Harbin Medical University, China Chinese Academy of Sciences; University of Chinese Academy of Sciences Beijing Tongren Hospital Capital Medical University Beijing China Department of Thoracic Surgery Beijing Tongren Hospital, Capital Medical University Beijing China Department of Vascular Surgery, The First Hospital of Qiqihar (The Affiliated Qiqihar Hospital of Southern Medical University), Qiqihar 161000, China Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA Tianjin Institute of Surveying and Mapping, Liqizhuang, Tianjin, China Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington, USA State Key Laboratory of Power Transmission Equipment and System Security and New Technology Chongqing University No.174 in Shazheng Street Shapingba District Chongqing 400044 P.R. China Department of Pharmacy, West China Hospital, Sichuan University, Chengdu 610041, China; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu 611137, China; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL, USA; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA Emergency Department The Second Affiliated Hospital of Chongqing Medical University Chongqing China Department of Pathology, Guiyang Maternal and Child Health Hospital , Guiyang City 550004 , Guizhou Province , China Department of Endocrinology, No.4 People's Hospital of Hengshui, Hengshui 053000. From the Rush Alzheimer's Disease Center (R.S.W., P.A.B., L.Y., S.E.A., A.S.B., J.A.S., D.A.B.) and Departments of Neurological Sciences (R.S.W., L.Y., A.S.B., J.A.S., D.A.B.), Behavioral Sciences (R.S.W., P.A.B.), and Pathology (J.A.S.), Rush University Medical Center, Chicago, IL; and Departments of Neurology and Emergency Medicine (S.R.L.), SUNY Downstate Medical Center, Brooklyn, NY. Department of Cardiovascular Medicine, Wujin Hospital Affiliated with Jiangsu University, Changzhou, Jiangsu, China; Department of Cardiovascular Medicine, The Wujin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, China College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China Ministry of Education of Key Laboratory of Energy Thermal Conversion and Control, School of Energy and Environment, Southeast University, China Guangzhou Tianhe District Hospital of TCM, Guangdong, China. for the TESTING Study Group Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China Innovative Transportation Research Institute, Texas Southern University, Houston, Texas, USA Rush Alzheimer’s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, P. R. China and the Writing Group for the Alzheimer’s Disease Genetics Consortium (ADGC) Jiangsu Provincial Key Laboratory of Solar Energy Science and Technology, School of Energy & Environment, Southeast University, Nanjing, 210096, China; Nanjing SolarU Energy Saving Technology Co., Ltd, Nanjing 210096, China School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035, China, and School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210089, China State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, China University of Petroleum, Beijing, 102249, China State Key Laboratory of Coordination Chemistry; Jiangsu Key Laboratory of Advanced Organic Materials; School of Chemistry and Chemical Engineering; Nanjing University; Nanjing 210023 Institute of Microbiology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30322, USA. Department of Chemistry and Biochemistry, Rowan University, Glassboro, New Jersey 08028, United States for the Chinese Acute Pancreatitis Clinical Trials Group (CAPCTG) Department of Emergency, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL USA; Rush University Medical Center Department of Neurological Sciences Chicago IL USA School of Chemistry and Chemical Engineering Yangzhou University Yangzhou 225002 P. R. China Liver Cancer Institute, Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University , Shanghai 200032 , China 1Department of Medical Biochemistry, Graduate School of Medicine, Tohoku University, Sendai, Japan. College of Veterinary Medicine, ‡Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, and §Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, Northeast Agricultural University, Harbin 150030, P.R. China Rush Alzheimer Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA Otolaryngology Department The Second Hospital of Hebei Medical University Shijiazhuang Hebei China |
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Total number of triples: 2575.